Department of Endocrinology and Diabetes, Diabetes Treatment Center, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Diabetes Metab J. 2014 Jun;38(3):220-9. doi: 10.4093/dmj.2014.38.3.220. Epub 2014 Jun 17.
Diabetes mellitus (DM) is associated with high mortality, morbidity, poor general health, and loss of health-related quality of life (HRQOL). The objective of the study was to assess the factors associated with HRQOL among patients with type 2 diabetes mellitus (T2DM).
This was a cross sectional study conducted among 283 T2DM patients during June 2011 and September 2012 at a major tertiary hospital in Riyadh, Saudi Arabia. The respondents were purposively and conveniently selected according to their availability during their routine visit to the outpatient clinics and they were interviewed using the Arabic version of the Short-Form 36-item survey (SF-36) to assess the HRQOL.
The mean age of the participants was 56.4±13.2 years. Around 63% (178) were males and 37% (105) were females. Glycosylated hemoglobin level was found to be significantly higher among female and HRQOL was higher among male. Respondents who were more than 50 years old had poor HRQOL than less than 50 years age group. Poor economic status, reported diabetic complications and longer duration of diabetes were significantly associated with poor HRQOL. The respondents treated with combination of therapies (oral medication plus insulin) indicated better HRQOL than patients with insulin therapy alone. Multivariate analysis indicated that gender, economic status (except subscale energy), and complications of DM (except subscale energy) as independent risk factor for HRQOL.
Gender, economic status, and complication of DM were independent risk factors for majority of the subscales of HRQOL.
糖尿病（DM）与高死亡率、高发病率、较差的总体健康状况以及健康相关生活质量（HRQOL）的丧失有关。本研究的目的是评估 2 型糖尿病（T2DM）患者 HRQOL 的相关因素。
这是一项横断面研究，于 2011 年 6 月至 2012 年 9 月在沙特阿拉伯利雅得的一家主要三级医院进行，共纳入 283 名 T2DM 患者。根据患者在常规门诊就诊时的可用性，有目的地选择和方便地选择了受访者，并使用阿拉伯语版的 36 项简短形式调查（SF-36）对他们进行访谈，以评估 HRQOL。
参与者的平均年龄为 56.4±13.2 岁。约 63%（178 人）为男性，37%（105 人）为女性。女性的糖化血红蛋白水平明显较高，而男性的 HRQOL 较高。年龄超过 50 岁的受访者的 HRQOL 比年龄小于 50 岁的受访者差。经济状况较差、报告有糖尿病并发症和糖尿病病程较长与较差的 HRQOL 显著相关。接受联合治疗（口服药物加胰岛素）的受访者的 HRQOL 优于单独接受胰岛素治疗的患者。多变量分析表明，性别、经济状况（除能量亚量表外）和糖尿病并发症（除能量亚量表外）是 HRQOL 的独立危险因素。
性别、经济状况和 DM 并发症是大多数 HRQOL 亚量表的独立危险因素。
