Laboratory of Virology, Department of Plant Sciences, Wageningen University Wageningen, Netherlands.
Front Plant Sci. 2014 Jun 27;5:307. doi: 10.3389/fpls.2014.00307. eCollection 2014.
To establish a successful infection plant viruses have to overcome a defense system composed of several layers. This review will overview the various strategies plants employ to combat viral infections with main emphasis on the current status of single dominant resistance (R) genes identified against plant viruses and the corresponding avirulence (Avr) genes identified so far. The most common models to explain the mode of action of dominant R genes will be presented. Finally, in brief the hypersensitive response (HR) and extreme resistance (ER), and the functional and structural similarity of R genes to sensors of innate immunity in mammalian cell systems will be described.
为了建立成功的感染,植物病毒必须克服由几个层次组成的防御系统。这篇综述将概述植物用来对抗病毒感染的各种策略,主要强调目前已鉴定出的针对植物病毒的单个显性抗性(R)基因和相应的无毒(Avr)基因的现状。将介绍解释显性 R 基因作用模式的最常见模型。最后,将简要描述过敏反应(HR)和极端抗性(ER),以及 R 基因与哺乳动物细胞系统先天免疫传感器的功能和结构相似性。