Tobias R S, Browne R M, Wilson C A
Department of Oral Pathology, University of Birmingham, Dental School, England.
J Prosthet Dent. 1989 Nov;62(5):601-5. doi: 10.1016/0022-3913(89)90087-5.
The difficulties associated with the disinfection of alginate (irreversible hydrocolloid) materials have resulted in the development of an irreversible hydrocolloid impression material impregnated with an antimicrobial compound, didecyldimethyl ammonium chloride. This investigation assessed the antibacterial and antifungal properties in vitro of this innovative irreversible hydrocolloid material by using the agar well technique. The microorganisms used were Pseudomonas aeruginosa, Streptococcus mutans, Streptococcus sanguis, Lactobacillus odontolyticus rodriguez, Actinomyces odontolyticus, mixed salivary organisms, and Candida albicans. The results showed an absence of activity against Pseudomonas aeruginosa. Varying degrees of antibacterial activity were exhibited against the other microorganisms. It is concluded that it is not know whether the limited antibacterial and antifungal effect demonstrated in this study is sufficient to prevent bacterial and fungal colonization of the impression surface in the mouth during clinical practice.
与藻酸盐(不可逆水胶体)材料消毒相关的困难促使了一种浸渍有抗菌化合物二癸基二甲基氯化铵的不可逆水胶体印模材料的研发。本研究通过琼脂孔技术评估了这种创新型不可逆水胶体材料的体外抗菌和抗真菌特性。所使用的微生物有铜绿假单胞菌、变形链球菌、血链球菌、罗德里格斯溶牙乳杆菌、溶牙放线菌、混合唾液微生物以及白色念珠菌。结果显示该材料对铜绿假单胞菌无活性。对其他微生物表现出不同程度的抗菌活性。结论是,尚不清楚本研究中所显示的有限抗菌和抗真菌作用是否足以在临床实践中防止口腔中印模表面的细菌和真菌定植。