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普那霉素与其他抗菌药物对生殖道病原体的体外活性比较

Comparative in vitro activities of pristinamycin and other antimicrobial agents against genital pathogens.

作者信息

Lefevre J C, Bauriaud R

机构信息

Laboratoire Central de Microbiologie, Hôpital Purpan, Toulouse, France.

出版信息

Antimicrob Agents Chemother. 1989 Dec;33(12):2152-4. doi: 10.1128/AAC.33.12.2152.

DOI:10.1128/AAC.33.12.2152
PMID:2515796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC172841/
Abstract

The MICs of pristinamycin for genital pathogens were compared with those of ampicillin, tetracycline, erythromycin, and ciprofloxacin. Pristinamycin was active against all the strains studied. Because of this activity and its lack of toxicity, pristinamycin might be a valuable therapeutic agent for treating major sexually transmitted diseases.

摘要

将普那霉素对生殖器病原体的最低抑菌浓度与氨苄西林、四环素、红霉素和环丙沙星的最低抑菌浓度进行了比较。普那霉素对所有研究的菌株均有活性。由于其活性以及缺乏毒性，普那霉素可能是治疗主要性传播疾病的一种有价值的治疗药物。

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本文引用的文献

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In-vitro comparison of macrolides, lincosamides and synergistins on Neisseria gonorrhoeae.
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Comparative in vitro activities of pristinamycin, its components, and other antimicrobial agents against anaerobic bacteria.普那霉素及其组分与其他抗菌药物对厌氧菌的体外比较活性
Antimicrob Agents Chemother. 1988 Jul;32(7):1094-6. doi: 10.1128/AAC.32.7.1094.
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[Surveillance of Neisseria gonorrhoeae strains isolated in Toulouse. In vitro antibiotic sensitivity and plasmid content].[图卢兹分离出的淋病奈瑟菌菌株的监测。体外抗生素敏感性和质粒含量]
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Lower genital tract infections in women: comparison of clinical and epidemiologic findings with microbiology.女性下生殖道感染：临床及流行病学发现与微生物学的比较
Sex Transm Dis. 1988 Apr-Jun;15(2):110-3. doi: 10.1097/00007435-198804000-00009.
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Antibiotics of the virginiamycin family, inhibitors which contain synergistic components.维吉尼亚霉素家族的抗生素，含有协同成分的抑制剂。
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