Nadeau Joshua M, Arnold Elysse B, Keene Amanda C, Collier Amanda B, Lewin Adam B, Murphy Tanya K, Storch Eric A
Department of Pediatrics, University of South Florida, 880 6th Street South, Box 7523, St. Petersburg, FL, 33701, USA,
Child Psychiatry Hum Dev. 2015 Aug;46(4):558-66. doi: 10.1007/s10578-014-0496-9.
Sleep-related problems (SRPs) are common and problematic among anxious youth but have not been investigated in anxious youth with autism spectrum disorder (ASD). Participants were 102 youth (ages 7-16 years) with ASD and comorbid anxiety. Youth and their primary caregiver were administered the Pediatric Anxiety Rating Scale. Parents completed the Multidimensional Anxiety Scale for Children-Parent (MASC-P) Report, Social Responsiveness Scale, and the Child Behavior Checklist (CBCL). A measure of SRPs was created from items from the CBCL and MASC-P. Results suggest SRPs were relatively common among youth with ASD and comorbid anxiety. The number of SRPs endorsed directly associated with parent ratings of social deficits, internalizing and externalizing symptoms, and anxiety symptoms, as well as with clinician-rated anxiety symptoms. Parent-rated internalizing symptoms predicted frequency of SRPs over and above social deficits, externalizing symptoms, and parent- and clinician-rated anxiety symptoms. A subset of 40 participants who completed family-based cognitive-behavioral therapy (CBT) experienced reduced SRPs following treatment. Implications, study limitations, and recommendations for future research are discussed.
睡眠相关问题（SRPs）在焦虑的青少年中很常见且成问题，但尚未在患有自闭症谱系障碍（ASD）的焦虑青少年中进行研究。研究参与者为102名患有ASD且合并焦虑症的青少年（年龄在7至16岁之间）。对青少年及其主要照顾者进行了儿童焦虑评定量表的评估。父母完成了儿童多维焦虑量表-父母报告（MASC-P）、社会反应量表和儿童行为检查表（CBCL）。通过CBCL和MASC-P中的项目创建了一项SRPs测量指标。结果表明，SRPs在患有ASD且合并焦虑症的青少年中相对常见。认可的SRPs数量与父母对社交缺陷、内化和外化症状以及焦虑症状的评分直接相关，也与临床医生评定的焦虑症状相关。父母评定的内化症状在社交缺陷、外化症状以及父母和临床医生评定的焦虑症状之外，还能预测SRPs的频率。完成基于家庭的认知行为疗法（CBT）的40名参与者在治疗后SRPs有所减少。本文讨论了研究的意义、局限性以及对未来研究的建议。
