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沙门氏菌噬菌体与原噬菌体:基因组学、分类学及应用方面

Salmonella phages and prophages: genomics, taxonomy, and applied aspects.

作者信息

Switt Andrea I Moreno, Sulakvelidze Alexander, Wiedmann Martin, Kropinski Andrew M, Wishart David S, Poppe Cornelis, Liang Yongjie

机构信息

Facultad de Ecología y Recursos Naturales, Universidad Andres Bello, Escuela de Medicina Veterinaria, Republica 440, 8370251, Santiago, Chile.

出版信息

Methods Mol Biol. 2015;1225:237-87. doi: 10.1007/978-1-4939-1625-2_15.

DOI:10.1007/978-1-4939-1625-2_15
PMID:25253259
Abstract

Since this book was originally published in 2007 there has been a significant increase in the number of Salmonella bacteriophages, particularly lytic virus, and Salmonella strains which have been fully sequenced. In addition, new insights into phage taxonomy have resulted in new phage genera, some of which have been recognized by the International Committee of Taxonomy of Viruses (ICTV). The properties of each of these genera are discussed, along with the role of phage as agents of genetic exchange, as therapeutic agents, and their involvement in phage typing.

摘要

自本书于2007年首次出版以来,沙门氏菌噬菌体的数量显著增加,尤其是裂解性病毒,并且已对大量沙门氏菌菌株进行了全基因组测序。此外,对噬菌体分类学的新见解催生了新的噬菌体属,其中一些已得到国际病毒分类委员会(ICTV)的认可。本文将讨论这些噬菌体属各自的特性,以及噬菌体作为基因交换媒介、治疗剂的作用,及其在噬菌体分型中的应用。

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