使用iSTAT和Piccolo分析仪进行即时检测与固定医院化学分析平台对非血清样本进行体液分析。
Bodily fluid analysis of non-serum samples using point-of-care testing with iSTAT and Piccolo analyzers versus a fixed hospital chemistry analytical platform.
作者信息
Londeree William, Davis Konrad, Helman Donald, Abadie Jude
机构信息
Department of Medicine, Tripler Army Medical Center, Honolulu, HI (WL).
出版信息
Hawaii J Med Public Health. 2014 Sep;73(9 Suppl 1):3-8.
INTRODUCTION
Forward deployed military medical units can provide sophisticated medical care with limited resources. Point-of-Care Testing (POCT) may facilitate care and expedite diagnosis. This study assessed the accuracy of results for POCT for non-serum samples (pleural, peritoneal, and cerebrospinal fluid) using iSTAT and Piccolo hand-held devices compared with results obtained using a hospital chemistry analyzer.
METHODS
Pleural, peritoneal, and cerebrospinal fluids obtained during routine care were simultaneously analyzed on a Vitros 5600 automated clinical chemistry hospital analyzer, iSTAT, and Piccolo POCT devices.
RESULTS
POCT results were highly correlated with the Vitros 5600 for pleural fluid LDH, glucose, and triglycerides (TG); for peritoneal fluid bilirubin, TG, glucose, albumin, and protein; and glucose for cerebrospinal fluid.
CONCLUSION
POCT results for non-serum samples from pleural, peritoneal, and cerebrospinal fluid correlate with standard hospital chemistry analysis. The results of this study demonstrate potential for possible new diagnostic roles for POCT in resource-limited environments.
引言
前沿部署的军事医疗单位能够在资源有限的情况下提供复杂的医疗服务。即时检验（POCT）可能有助于医疗服务并加快诊断。本研究评估了使用iSTAT和Piccolo手持式设备对非血清样本（胸腔积液、腹腔积液和脑脊液）进行POCT检测结果的准确性，并与使用医院化学分析仪获得的结果进行比较。
方法
在常规护理过程中获取的胸腔积液、腹腔积液和脑脊液同时在Vitros 5600自动化临床化学医院分析仪、iSTAT和Piccolo POCT设备上进行分析。
结果
POCT检测结果与Vitros 5600对胸腔积液乳酸脱氢酶（LDH）、葡萄糖和甘油三酯（TG）；腹腔积液胆红素、TG、葡萄糖、白蛋白和蛋白质；以及脑脊液葡萄糖的检测结果高度相关。
结论
胸腔积液、腹腔积液和脑脊液非血清样本的POCT检测结果与标准医院化学分析结果相关。本研究结果表明POCT在资源有限环境中可能具有新的诊断作用。
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