巴西首次报告产NDM-1的鲍曼不动杆菌序列型25。
First report of NDM-1-producing Acinetobacter baumannii sequence type 25 in Brazil.
作者信息
Pillonetto Marcelo, Arend Lavinia, Vespero Eliana Carolina, Pelisson Marsileni, Chagas Thiago Pavoni Gomes, Carvalho-Assef Ana Paula D'Alincourt, Asensi Marise Dutra
机构信息
Pontifical Catholic University, School of Health and Biosciences, Curitiba, PR, Brazil State Central Public Health Laboratory, São José dos Pinhais, PR, Brazil
State Central Public Health Laboratory, São José dos Pinhais, PR, Brazil.
出版信息
Antimicrob Agents Chemother. 2014 Dec;58(12):7592-4. doi: 10.1128/AAC.03444-14. Epub 2014 Oct 6.
Abstract
New Delhi metallo-β-lactamase 1 (NDM-1) was first identified in Brazil in Enterobacter hormaechei and Providencia rettgeri in 2013. Here, we describe the first case of NDM-1-producing Acinetobacter baumannii sequence type 25 isolated from the urinary tract of a 71-year-old man who died of multiple complications, including A. baumannii infection. The NDM-1 gene was detected by quantitative PCR, and its sequence confirmed its presence in an ∼ 100-kb plasmid.
摘要
新德里金属β-内酰胺酶1（NDM-1）于2013年在巴西首次从霍氏肠杆菌和雷氏普罗威登斯菌中被鉴定出来。在此，我们描述了首例从一名死于包括鲍曼不动杆菌感染在内的多种并发症的71岁男性尿路中分离出的产NDM-1的序列型25鲍曼不动杆菌。通过定量PCR检测到NDM-1基因，其序列证实它存在于一个约100kb的质粒中。
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