Delaney Christopher L, Miller Michelle D, Dickinson Kacie M, Spark J Ian
Department of Nutrition and Dietetics, Flinders University, Adelaide, Australia.
Nutr J. 2014 Oct 15;13:100. doi: 10.1186/1475-2891-13-100.
Presence of numerous diet responsive comorbidities and high atherosclerotic burden among adults with intermittent claudication demands attention is given to diet in an effort to delay progression of peripheral artery disease. The aim of this study was to compare diet of adults with intermittent claudication: (a) against dietary recommendations; (b) following 12 weeks of supervised exercise training; and (c) against non-peripheral artery disease controls.
Diet was assessed using a food frequency questionnaire pre and post supervised exercise training. Pre-exercise diet was compared against Suggested Dietary Targets and against non-peripheral artery disease controls matched for gender, age and body weight. Pre-exercise diet was also compared against post-exercise diet.
Pre-exercise 25/31 participants, 5/31 participants, 16/31 participants and 4/31 participants achieved recommendations for protein, carbohydrate, total fat and saturated fat respectively. Few achieved recommended intakes for fibre (3/31 participants), cholesterol (8/31 participants), folate (11/31 participants), potassium (1/31 participants), sodium (4/31 participants), retinol equivalents (1/31 participants) and vitamin C (3/31 participants). There were no differences observed between participants compared to controls in achievement of recommendations. Post-exercise, marginally more participants were able to achieve targets for cholesterol, sodium and vitamin C but not for any other nutrients.
Despite evidence to support benefits of dietary modification in risk reduction of peripheral artery disease, adults with intermittent claudication continue to consume poor diets. Research is required to determine whether dietary changes can be achieved with greater attention to nutrition counselling and the impact assessed in terms of delayed disease progression and long term health outcomes.
ClinicalTrials.gov: NCT01871779.
间歇性跛行的成年人存在多种饮食反应性合并症且动脉粥样硬化负担较高，因此需要关注饮食，以延缓外周动脉疾病的进展。本研究的目的是比较间歇性跛行成年人的饮食情况：(a)与饮食建议相比；(b)在接受12周的监督运动训练后；(c)与非外周动脉疾病对照组相比。
在监督运动训练前后，使用食物频率问卷评估饮食情况。将运动前的饮食与建议膳食目标以及按性别、年龄和体重匹配的非外周动脉疾病对照组进行比较。运动前的饮食也与运动后的饮食进行比较。
运动前，分别有25/31、5/31、16/31和4/31的参与者达到了蛋白质、碳水化合物、总脂肪和饱和脂肪的建议摄入量。很少有人达到纤维（3/31参与者）、胆固醇（8/31参与者）、叶酸（11/31参与者）、钾（1/31参与者）、钠（4/31参与者）、视黄醇当量（1/31参与者）和维生素C（3/31参与者）的建议摄入量。与对照组相比，参与者在达到建议摄入量方面没有差异。运动后，略多的参与者能够达到胆固醇、钠和维生素C的目标，但其他营养素均未达到。
尽管有证据支持饮食调整对降低外周动脉疾病风险有益，但间歇性跛行的成年人饮食仍然不佳。需要开展研究以确定，通过更多地关注营养咨询是否可以实现饮食改变，以及评估其对延缓疾病进展和长期健康结果的影响。
ClinicalTrials.gov：NCT01871779。
