Czyżewski Lukasz, Sańko-Resmer Joanna, Wyzgał Janusz, Kurowski Andrzej
Department of Anaesthesiology, Institute of Cardiology, Warsaw, Poland.
Department of Nephrological Nursing, Medical University of Warsaw, Warsaw, Poland.
Ann Transplant. 2014 Nov 9;19:576-85. doi: 10.12659/AOT.891265.
The quality of life may determine the efficacy of renal replacement therapy (RRT). The purpose of the study was to compare the health-related quality of life (HRQOL) of end-stage renal disease (ESRD) patients depending on RRT method.
MATERIAL/METHODS: The studies were conducted on 120 patients divided into 3 groups depending on RRT method: 30 peritoneal dialysis (PD) patients, 40 hemodialysis (HD) patients, and 47 post-kidney transplantation (KTx) patients. The following research tools were used: (1) Medical Outcomes Study 36 - the Short Form (SF-36 v.1); (2) Kidney Disease Quality of Life Short Form (KDQOL-SF™ v.1.3); and (3) disease history. The relevance level was p<0.05.
The evaluation of PCS by HD and PD patients is poorer compared to patients in the 3rd and 12th month after KTx (34.7 ± 7.4 vs. 37.51 ± 10.63 vs. 45.01 ± 9.43 vs. 45.55 ± 8.62; p<0.05; respectively). PCS statistically significantly correlated with the following: SBP (r=-0.54; p<0.05), DBP (r=-0.58; p<0.05), and creatinine concentration (r=0.46; p<0.05) in the 12(th) month after KTx.
HRQOL of ESRD patients differed depending on the RRT method: top values were shown by post-KTx patients, lower by PD patients, and the bottom ones by HD patients. Along with patient age, increased BP, and BMI, a drop in value of HRQOL in post-Tx or PD patients was observed. When choosing RTT method, patients may use the results of the evaluation of quality of life. A preferred lifestyle, and predominantly the work status and quality of social interaction, should decide the choice of treatment.
生活质量可能决定肾脏替代治疗（RRT）的疗效。本研究的目的是比较终末期肾病（ESRD）患者基于RRT方法的健康相关生活质量（HRQOL）。
材料/方法：对120例患者进行研究，根据RRT方法将其分为3组：30例腹膜透析（PD）患者、40例血液透析（HD）患者和47例肾移植（KTx）术后患者。使用了以下研究工具：（1）医学结局研究简表36（SF - 36 v.1）；（2）肾脏病生活质量简表（KDQOL - SF™ v.1.3）；以及（3）疾病史。显著性水平为p<0.05。
与KTx术后第3个月和第12个月的患者相比，HD和PD患者的PCS评估较差（分别为34.7±7.4 vs. 37.51±10.63 vs. 45.01±9.43 vs. 45.55±8.62；p<0.05）。在KTx术后第12个月，PCS与以下因素在统计学上显著相关：收缩压（r = -0.54；p<0.05）、舒张压（r = -0.58；p<0.05）和肌酐浓度（r = 0.46；p<0.05）。
ESRD患者的HRQOL因RRT方法而异：KTx术后患者的HRQOL最高，PD患者较低，HD患者最低。随着患者年龄、血压升高和体重指数增加，观察到Tx术后或PD患者的HRQOL值下降。在选择RTT方法时，患者可以参考生活质量评估结果。首选的生活方式，主要是工作状态和社会互动质量，应决定治疗的选择。
