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我们是否遗漏了妊娠期间的肥厚型心肌病?一家三级护理医院的经验。

Are we missing hypertrophic cardiomyopathy in pregnancy? Experience of a tertiary care hospital.

作者信息

Sikka Pooja, Suri Vanita, Aggarwal Neelam, Chopra Seema, Bahl Ajay, Vijayverghia Rajesh

机构信息

Assistant Professor, Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .

Professor, Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .

出版信息

J Clin Diagn Res. 2014 Sep;8(9):OC13-5. doi: 10.7860/JCDR/2014/9924.4803. Epub 2014 Sep 20.

Abstract

BACKGROUND

Controversies persist regarding risks associated with pregnancy and delivery in women with hypertrophic cardiomyopathy (HCM). To date, pregnancy outcome data for these patients is scarce. We report the experience of pregnancies with HCM in a tertiary care hospital.

MATERIALS AND METHODS

Data regarding cardiac illness and obstetric profile of all women attending the cardio-obstetrics clinic from January 1990 to December 2012 were studied. The records of cardiac illness of all women were checked and all patients with HCM were included in the study.

RESULTS

Out of total 2016 patients booked in the cardio-obstetrics clinic between 1990 and 2012, only 4 women were found to have a diagnosis of HCM (0.2%). Of these, 2 women with left ventricular outflow tract obstruction and one with non-obstructive HCM had only mild symptoms and tolerated pregnancy and labour well. One patient had HCM with restrictive physiology developed heart failure and intra-uterine fetal death.

CONCLUSION

HCM is underdiagnosed and rarely identified in pregnancy. Most patients with HCM tolerated pregnancy well, howeverone patient with restrictive physiology developed heart failure during her first pregnancy.

摘要

背景

肥厚型心肌病(HCM)女性患者妊娠和分娩相关风险仍存在争议。迄今为止,这些患者的妊娠结局数据稀缺。我们报告一家三级医疗中心医院HCM患者的妊娠情况。

材料与方法

研究了1990年1月至2012年12月期间所有前往心脏产科门诊就诊女性的心脏病及产科资料。检查了所有女性的心脏病记录,所有HCM患者均纳入研究。

结果

在1990年至2012年间心脏产科门诊登记的2016例患者中,仅4例女性被诊断为HCM(0.2%)。其中,2例左心室流出道梗阻女性和1例非梗阻性HCM女性仅有轻微症状,妊娠和分娩耐受性良好。1例具有限制性生理学特征的HCM患者发生心力衰竭和宫内胎儿死亡。

结论

HCM在孕期诊断不足且很少被识别。大多数HCM患者妊娠耐受性良好,然而1例具有限制性生理学特征的患者在首次妊娠期间发生心力衰竭。

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