端粒的深远影响。
The long reach of telomeres.
作者信息
Misteli Tom
机构信息
National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
出版信息
Genes Dev. 2014 Nov 15;28(22):2445-6. doi: 10.1101/gad.254573.114.
Abstract
The primary purpose of telomeres is to protect chromosome ends from erosion during cell division cycles. New observations suggest an additional function for telomeres, namely in gene silencing via formation of long-range chromatin interactions.
摘要
端粒的主要功能是在细胞分裂周期中保护染色体末端免受侵蚀。新的观察结果表明端粒还有另外一个功能，即通过形成长距离染色质相互作用来实现基因沉默。
Zotero 插件