Komoto Satoshi, Pongsuwanna Yaowapa, Ide Tomihiko, Wakuda Mitsutaka, Guntapong Ratigorn, Dennis Francis Ekow, Haga Kei, Fujii Yoshiki, Katayama Kazuhiko, Taniguchi Koki
Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan.
Virus Research Institute, Department of Medical Sciences, National Institute of Health, Nonthaburi 11000, Thailand.
Vet Microbiol. 2014 Dec 5;174(3-4):577-583. doi: 10.1016/j.vetmic.2014.09.033. Epub 2014 Oct 14.
Porcine group A rotavirus (RVA) strain P343 (RVA/Pig-tc/THA/P343/1991/G10P[5]) was suggested to have VP7 and VP4 genes of bovine origin. In order to obtain precise information on the exact origin and evolution of this unusual porcine strain, the remaining nine genes (VP6, VP1-3, and NSP1-5) of strain P343 were sequenced and analyzed in the present study. On whole genomic analysis, strain P343 was found to have a bovine RVA-like genotype constellation (G10-P[5]-I2-R2-C2-M2-A3-N2-T6-E2-H3) different from those of typical porcine RVA strains. Furthermore, on phylogenetic analysis, each of the 11 genes of strain P343 appeared to be of bovine origin. Therefore, strain P343 was suggested to be a bovine RVA strain that was transmitted to pigs.
猪A组轮状病毒（RVA）毒株P343（RVA/Pig-tc/THA/P343/1991/G10P[5]）被认为具有牛源的VP7和VP4基因。为了获得关于这种不寻常猪毒株的确切起源和进化的精确信息，本研究对毒株P343的其余九个基因（VP6、VP1 - 3和NSP1 - 5）进行了测序和分析。通过全基因组分析，发现毒株P343具有与典型猪RVA毒株不同的牛RVA样基因型组合（G10 - P[5] - I2 - R2 - C2 - M2 - A3 - N2 - T6 - E2 - H3）。此外，在系统发育分析中，毒株P343的11个基因中的每一个似乎都源自牛。因此，毒株P343被认为是一种传播给猪的牛RVA毒株。
