Levitsky Dmitri O, Dembitsky Valery M
Unité Fonctionalité et Ingénierie des Protéines (UFIP), Faculté des Sciences et des Techniques, Université de Nantes/CNRS, 44322, Nantes Cedex 03, France.
Nat Prod Bioprospect. 2014 Dec 3;5(1):1-16. doi: 10.1007/s13659-014-0048-9.
Upon emergence of modern anticancer therapy, medical community is divided into two opposite camps, one of them claiming absolute necessity of using isolated or synthesized chemical compounds for efficient patient treatment and another one advocating alternative cancer therapies, in particular those based on natural sources, including extracts from plants. It seems, in reality, that the two camps are reconcilable: while natural sources, plant extracts or juices play both curative and protective role, drugs represent the ultimate possibility to inhibit or reverse tumor development. In this paper we tried to analyze anti-breast cancer potencies of quite a few extracts from different plant sources and to compare their anti-proliferative efficiency of crude extracts with actions of their purified ingredients.
随着现代抗癌疗法的出现，医学界分为两个对立的阵营，其中一方声称使用分离或合成的化合物对患者进行有效治疗是绝对必要的，而另一方则主张采用替代癌症疗法，特别是那些基于天然来源的疗法，包括植物提取物。实际上，这两个阵营似乎是可以调和的：虽然天然来源、植物提取物或汁液兼具治疗和保护作用，但药物是抑制或逆转肿瘤发展的最终手段。在本文中，我们试图分析来自不同植物来源的多种提取物的抗乳腺癌潜力，并比较其粗提物的抗增殖效率与其纯化成分的作用。
