Sulaiman H A
Department of Internal Medicine, University of Indonesia Faculty of Medicine, Jakarta.
Gastroenterol Jpn. 1989 Aug;24(4):434-41. doi: 10.1007/BF02774353.
The relationship between hepatitis B virus (HBV) infection and 144 cases with liver cirrhosis (LC) and 82 cases with hepatocellular carcinoma (HCC), admitted to the Department of Internal Medicine, Dr. Cipto Mangunkusmo Hospital in Jakarta, was investigated within the period from January 1 until December 31, 1984. The prevalence of HBsAg in 144 cases with LC was 41.1%, anti-HBs 33.3% and anti-HBc alone 16.0%. In only 9.0% no markers were found. The prevalence of HBeAg in 60 cases HBsAg positive LC was 35.0%, anti-HBe was 41.7% and in 23.3% both markers were negative. Among 82 cases with HCC, the prevalence of HBsAg was 47.6%, anti-HBs was 25.6% and anti-HBc alone was 15.9%. The prevalence of HBeAg in 39 cases with HCC was 25.6%, anti-HBe was 51.3% and in 23.1% both markers were negative. Age distribution between HBsAg positive and negative in LC was observed significant difference (P less than 0.05). Mean age of HBsAg positive group in LC was 5 years younger than that of the HBsAg negative group.
1984年1月1日至12月31日期间，对雅加达西托·曼贡库斯莫医院内科收治的144例肝硬化（LC）患者和82例肝细胞癌（HCC）患者与乙型肝炎病毒（HBV）感染之间的关系进行了调查。144例LC患者中，HBsAg阳性率为41.1%，抗-HBs阳性率为33.3%，单纯抗-HBc阳性率为16.0%。仅9.0%未发现标志物。60例HBsAg阳性的LC患者中，HBeAg阳性率为35.0%，抗-HBe阳性率为41.7%，两种标志物均阴性的占23.3%。82例HCC患者中，HBsAg阳性率为47.6%，抗-HBs阳性率为25.6%，单纯抗-HBc阳性率为15.9%。39例HCC患者中，HBeAg阳性率为25.6%，抗-HBe阳性率为51.3%，两种标志物均阴性的占23.1%。观察到LC患者中HBsAg阳性和阴性的年龄分布存在显著差异（P小于0.05）。LC患者中HBsAg阳性组的平均年龄比HBsAg阴性组小5岁。
