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正常健康献血者全血献血不良反应的研究:查谟地区三级医疗中心的经验

Study of adverse whole blood donor reactions in normal healthy blood donors: experience of tertiary health care centre in jammu region.

作者信息

Dogra Ashu, Sidhu Meena, Dogra Mitu, Raina Tilak Raj

机构信息

Department of Transfusion Medicine, Government Medical College, Jammu, Jammu, India.

Department of Pathology, Government Medical College, Jammu, Jammu, India.

出版信息

Indian J Hematol Blood Transfus. 2015 Mar;31(1):142-5. doi: 10.1007/s12288-014-0396-y. Epub 2014 May 8.

Abstract

Whole blood donation is generally a safe procedure, but sometimes adverse reactions of varying severity may occur during or at completion of blood donation process. The aim of the present study was to estimate the frequency and type of adverse events during blood donation. This retrospective study conducted from November 2011 to December 2012 at Department of Blood Transfusion Medicine GMC Jammu. All whole blood donations at our Department was analyzed. All adverse events occurring during or at end of donation were noted using standardized format. Overall 108 adverse events were reported in relation to 29,524 donations, resulting in overall adverse event rate of 0.365 %. Presyncopal reactions in other words vasovagal reactions of mild intensity, were the most commonly observed adverse reactions and accounted for approximately 58/108 (53.70 %) of all adverse reactions noted. Only 0.365 % of blood donations were complicated by adverse events and most of these events were presyncopal symptoms. Our study reinforces that blood donation is a very safe procedure which could be made even more event free by following certain friendly, reassuring and tactful practices.

摘要

全血捐献通常是一个安全的过程,但有时在献血过程中或献血结束时可能会发生不同严重程度的不良反应。本研究的目的是估计献血过程中不良事件的发生率和类型。这项回顾性研究于2011年11月至2012年12月在查谟政府医学院输血医学科进行。对我们科室的所有全血捐献进行了分析。使用标准化表格记录献血过程中或献血结束时发生的所有不良事件。在29524次捐献中,共报告了108起不良事件,不良事件总发生率为0.365%。晕厥前期反应,即轻度血管迷走神经反应,是最常观察到的不良反应,约占所有记录到的不良反应的58/108(53.70%)。只有0.365%的献血会出现不良事件,其中大多数是晕厥前期症状。我们的研究强化了献血是一个非常安全的过程这一观点,通过遵循某些友好、安心且得体的做法,献血过程可以更加无不良事件发生。

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Blood Transfus. 2011 Jan;9(1):46-9. doi: 10.2450/2010.0002-10. Epub 2010 Sep 7.

本文引用的文献

2
Adverse reactions in whole blood donors: an Indian scenario.全血献血者的不良反应:印度情况。
Blood Transfus. 2011 Jan;9(1):46-9. doi: 10.2450/2010.0002-10. Epub 2010 Sep 7.
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Complications related to blood donation: a population-based study.与献血相关的并发症:一项基于人群的研究。
Vox Sang. 2008 Feb;94(2):132-7. doi: 10.1111/j.1423-0410.2007.01000.x. Epub 2007 Nov 19.
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Blood donation-related neurologic needle injury: evaluation of 2 years' worth of data from a large blood center.
Transfusion. 1996 Mar;36(3):213-5. doi: 10.1046/j.1537-2995.1996.36396182137.x.
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Convulsive syncope in blood donors.献血者的惊厥性晕厥
Ann Neurol. 1982 May;11(5):525-8. doi: 10.1002/ana.410110513.
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Development of arteriovenous fistula following blood donation.献血后动静脉瘘的形成
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