Department of Pathology, Lady Hardinge Medical College, New Delhi, India.
Blood Transfus. 2011 Jan;9(1):46-9. doi: 10.2450/2010.0002-10. Epub 2010 Sep 7.
Whole blood donation is generally considered to be a safe procedure, but occasionally adverse reactions of varying severity may occur during or at the end of the collection. The aim of the study was to estimate the frequency and type of adverse events occurring during blood donation and to assess the practices which would help to minimise them.
This retrospective single-centre study was conducted from June 2007 to November 2009 at a regional blood transfusion centre. All whole blood donations made at the centre were analysed. All adverse events occurring during or at the end of donation were noted using a standardised format.
Overall 113 adverse events were reported in relation to 19,045 donations, resulting in an overall adverse event rate of 0.6%, that is, an incidence of 1 in every 166 donations. Presyncopal symptoms, in other words vasovagal reactions of mild intensity, were the most commonly observed adverse reactions and accounted for approximately 70% of all adverse reactions noted.
Only 0.6% of blood donations were complicated by adverse events and most of these events were presyncopal symptoms. Our study reinforces the fact that blood donation is a very safe procedure which could be made even more event-free by following certain friendly, reassuring and tactful practices.
全血捐献通常被认为是安全的，但在采集过程中或结束时偶尔会出现不同严重程度的不良反应。本研究的目的是评估献血过程中发生不良反应的频率和类型，并评估有助于减少这些不良反应的措施。
这是一项回顾性单中心研究，于 2007 年 6 月至 2009 年 11 月在一个地区输血中心进行。对中心的所有全血捐献进行了分析。使用标准化格式记录了在捐献过程中或结束时发生的所有不良反应。
共有 113 例不良反应与 19045 次献血有关，总不良反应发生率为 0.6%，即每 166 次献血中就有 1 次发生不良反应。前驱症状，即轻度血管迷走神经性反应，是最常见的不良反应，约占所有不良反应的 70%。
只有 0.6%的献血出现不良反应，其中大多数为前驱症状。我们的研究进一步证实了献血是一种非常安全的过程，通过遵循某些友好、安慰和机智的措施，可以使其更加无不良反应。
