用于灵敏的微尺度化学和生化传感的二维光子晶体
Two-dimensional photonic crystals for sensitive microscale chemical and biochemical sensing.
作者信息
Baker James E, Sriram Rashmi, Miller Benjamin L
机构信息
Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627 , USA.
Department of Biomedical Engineering, University of Rochester, Rochester, NY 14627, USA.
出版信息
Lab Chip. 2015 Feb 21;15(4):971-990. doi: 10.1039/c4lc01208a.
Abstract
Photonic crystals - optical devices able to respond to changes in the refractive index of a small volume of space - are an emerging class of label-free chemical- and bio-sensors. This review focuses on one class of photonic crystal, in which light is confined to a patterned planar material layer of sub-wavelength thickness. These devices are small (on the order of tens to hundreds of microns square), suitable for incorporation into lab-on-a-chip systems, and in theory can provide exceptional sensitivity. We introduce the defining characteristics and basic operation of two-dimensional photonic crystal sensors, describe variations of their basic design geometry, and summarize reported detection results from chemical and biological sensing experiments.
摘要
光子晶体——能够对小体积空间内折射率变化做出响应的光学器件——是一类新兴的无标记化学和生物传感器。本综述聚焦于一类光子晶体，其中光被限制在亚波长厚度的图案化平面材料层中。这些器件体积小（尺寸在几十到几百微米见方），适合集成到芯片实验室系统中，并且理论上能够提供卓越的灵敏度。我们介绍二维光子晶体传感器的定义特性和基本操作，描述其基本设计几何结构的变化，并总结化学和生物传感实验中已报道的检测结果。
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