发酵念珠菌作为一名早产新生儿持续性真菌血症的病因，通过两性霉素B和卡泊芬净联合治疗成功治愈。
Candida fermentati as a cause of persistent fungemia in a preterm neonate successfully treated by combination therapy with amphotericin B and caspofungin.
作者信息
Al-Sweih Noura, Ahmad Suhail, Joseph Leena, Khan Seema, Vayalil Sandhya, Chandy Rachel, Khan Ziauddin
机构信息
Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait Maternity Hospital, Shuwaikh, Kuwait.
Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait.
出版信息
J Clin Microbiol. 2015 Mar;53(3):1038-41. doi: 10.1128/JCM.03351-14. Epub 2015 Jan 7.
Abstract
A case of persistent candidemia in a preterm neonate caused by Candida fermentati, identified by sequencing of the internally transcribed spacer region of ribosomal DNA (rDNA), is described. The neonate was treated for 30 days by combination therapy with amphotericin B (AmBisome) and caspofungin with a successful outcome, and no drug-related side effects were observed.
摘要
本文描述了一例由发酵念珠菌引起的早产新生儿持续性念珠菌血症病例，该病例通过核糖体DNA（rDNA）内转录间隔区测序得以确诊。该新生儿接受了两性霉素B（安必素）和卡泊芬净联合治疗30天，治疗成功，未观察到与药物相关的副作用。
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