Vanegas Jose C, Afeiche Myriam C, Gaskins Audrey J, Mínguez-Alarcón Lidia, Williams Paige L, Wright Diane L, Toth Thomas L, Hauser Russ, Chavarro Jorge E
School of Medicine, Pontificia Universidad Javeriana, Bogota, Colombia.
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts.
Fertil Steril. 2015 Mar;103(3):749-55.e2. doi: 10.1016/j.fertnstert.2014.12.104. Epub 2015 Jan 7.
To study the relation of dietary phytoestrogens intake and clinical outcomes of women undergoing infertility treatment with the use of assisted reproductive technology (ART).
Prospective cohort study.
Fertility center.
PATIENT(S): A total of 315 women who collectively underwent 520 ART cycles from 2007 to 2013.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Implantation, clinical pregnancy, and live birth rates per initiated cycle.
RESULT(S): Soy isoflavones intake was positively related to live birth rates in ART. Compared with women who did not consume soy isoflavones, the multivariable-adjusted odds ratios of live birth (95% confidence interval) for women in increasing categories of soy isoflavones intake were 1.32 (0.76-2.27) for women consuming 0.54-2.63 mg/d, 1.87 (1.12-3.14) for women consuming 2.64-7.55 mg/d, and 1.77 (1.03-3.03) for women consuming 7.56-27.89 mg/d.
CONCLUSION(S): Dietary soy intake was positively related to the probability of having a live birth during infertility treatment with ART.
研究膳食植物雌激素摄入量与接受辅助生殖技术（ART）治疗的不孕女性临床结局之间的关系。
前瞻性队列研究。
生育中心。
2007年至2013年期间共有315名女性共接受了520个ART周期治疗。
无。
每个启动周期的着床率、临床妊娠率和活产率。
大豆异黄酮摄入量与ART治疗中的活产率呈正相关。与未摄入大豆异黄酮的女性相比，大豆异黄酮摄入量递增的女性活产的多变量调整优势比（95%置信区间）为：摄入0.54 - 2.63毫克/天的女性为1.32（0.76 - 2.27），摄入2.64 - 7.55毫克/天的女性为1.87（1.12 - 3.14），摄入7.56 - 27.89毫克/天的女性为1.77（1.03 - 3.03）。
在接受ART治疗的不孕过程中，膳食大豆摄入量与活产概率呈正相关。
