Wootton Landon, Holmes Charles, Sahoo Narayan, Beddar Sam
Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas, USA.
Phys Med Biol. 2015 Feb 7;60(3):1185-98. doi: 10.1088/0031-9155/60/3/1185. Epub 2015 Jan 15.
We tested the feasibility of using plastic scintillation detectors (PSDs) for proton entrance dosimetry. A PSD built with BCF-12 scintillating fiber was used to measure the absolute entrance dose of a passively scattered proton beam for energies ranging from 140 to 250 MeV, and for a range of spread out Bragg peak (SOBP) widths at two energies, to quantify the effect of ionization quenching on the response of the detector and to determine the necessity of Cerenkov radiation correction in proton beams. The overall accuracy and precision of the PSD was evaluated by measuring lateral beam profiles and comparing the results with profiles measured using film. The PSD under-responded owing to ionization quenching, exhibiting approximately a 7% loss of signal at the highest energy studied (250 MeV) and a 10% loss of signal at the lowest energy studied (140 MeV). For a given nominal energy, varying the SOBP width did not significantly alter the response of the PSD. Cerenkov radiation contributed negligibly to the PSD signal and can be safely ignored without introducing more than 1% error in the measured dose. Profiles measured with the PSD and film agreed to within the uncertainty of the detector, demonstrating good relative accuracy. Although correction factors were necessary to account for ionization quenching, the magnitude of the correction varied minimally over a broad range of energies; PSDs therefore represent a practical detector for proton entrance dosimetry.
我们测试了使用塑料闪烁探测器(PSD)进行质子入射剂量测定的可行性。使用由BCF - 12闪烁光纤构建的PSD来测量能量范围为140至250 MeV的被动散射质子束的绝对入射剂量,以及在两种能量下一系列扩展布拉格峰(SOBP)宽度的情况,以量化电离猝灭对探测器响应的影响,并确定质子束中切伦科夫辐射校正的必要性。通过测量束流横向轮廓并将结果与使用胶片测量的轮廓进行比较,评估了PSD的整体准确性和精度。由于电离猝灭,PSD响应不足,在研究的最高能量(250 MeV)下信号损失约7%,在研究的最低能量(140 MeV)下信号损失10%。对于给定的标称能量,改变SOBP宽度不会显著改变PSD的响应。切伦科夫辐射对PSD信号的贡献可忽略不计,在测量剂量中忽略它不会引入超过1%的误差。用PSD和胶片测量的轮廓在探测器的不确定度范围内一致,显示出良好的相对准确性。虽然需要校正因子来考虑电离猝灭,但校正幅度在很宽的能量范围内变化很小;因此,PSD是质子入射剂量测定的一种实用探测器。