Yunus A, Seet W, Mohamad Adam B, Haniff J
Malays Fam Physician. 2013 Apr 30;8(1):5-11. eCollection 2013.
To validate the Malay version of Berlin Questionnaire (BQ) as a tool to screen for patients at risk of obstructive sleep apnea (OSA) in primary care.
Most patients with OSA are unrecognised and untreated. Thus, the BQ has been used as a tool to screen for patients at risk for OSA. However, this tool has not been validated in Malay version.
A parallel back-to-back translation method was applied to produce the Malay version (Berlin-M). The Malay version was administered to 150 patients in a tertiary respiratory medical centre. Concurrent validity of the Berlin-M was determined using the Apnea Hypopnea Index (AHI) as the gold standard measure. The test-retest reliability and internal consistency of the Berlin-M were determined.
Most patients were males (64.0%) and majority of them were Malays (63.3%). Based on the sleep study test, 121 (84.0%) were classified as high risk while 23 (16.0%) as low risk using the Apnea Hypopnea Index (AHI) ≥5 as the cutoff point. The test-retest reliability Kappa value showed a good range between 0.864 - 1.000. The Cronbach's alpha of BQ was 0.750 in category 1 and 0.888 in category 2. The sensitivity and specificity were 92% and 17% respectively.
The BQ showed high sensitivity (92%) but low specificity (17%). Therefore, though the Berlin-M is useful as a screening tool, it is not a confirmatory diagnostic tool.
验证马来语版柏林问卷（BQ）作为基层医疗中筛查阻塞性睡眠呼吸暂停（OSA）高危患者的工具。
大多数OSA患者未被识别和治疗。因此，BQ已被用作筛查OSA高危患者的工具。然而，该工具的马来语版本尚未经过验证。
采用平行背对背翻译方法制作马来语版（柏林-M）。在一家三级呼吸医学中心对150名患者进行了马来语版问卷调查。以呼吸暂停低通气指数（AHI）作为金标准测量方法，确定柏林-M的同时效度。确定柏林-M的重测信度和内部一致性。
大多数患者为男性（64.0%），其中大多数是马来人（63.3%）。根据睡眠研究测试，以呼吸暂停低通气指数（AHI）≥5为截断点，121名（84.0%）被归类为高危，23名（16.0%）为低危。重测信度Kappa值在0.864 - 1.000之间，显示出良好的范围。BQ的Cronbach's alpha系数在第1类中为0.750，在第2类中为0.888。敏感性和特异性分别为92%和17%。
BQ显示出高敏感性（92%）但低特异性（17%）。因此，虽然柏林-M作为一种筛查工具是有用的，但它不是一种确诊诊断工具。
