Papatsiros Vassilis
Department of Medicine (Clinic of Farm Animal Medicine), Faculty of Veterinary Medicine, University of Thessaly, Karditsa, Greece.
Vet Res Forum. 2012 Summer;3(3):217-20.
Porcine necrotic ear syndrome (PNES) in pigs has been reported as an increasing health problem in many countries with intensive pig farming. The etiology of this disease is complex and the presumed triggering factors can be divided into infectious and non-infectious agents. The present report describes a case of Porcine Circovirus type 2 (PCV2), infection associated with lesions of PNES at the weaning stage of a farrow-to-finish pig farm. Approximately 35% of weaners (1-3 weeks after weaning) presented clinical symptoms similar to Post-weaning Multisystemic Wasting Syndrome (PMWS). About 2-3 weeks after weaning the first lesions of PNES occurred in approximately 20% of pigs, resulting in a significant health problem characterized by poor growth or severe wasting and finally mortality up to 15% in some batches. Moreover, approximately 5% of survived weaners, during growing / finishing stage, presented poor growth and secondary co-infections that lead to death. The present study based on the clinical signs, serological and pathological examinations, indicates that weaners suffered by sub-acute PCV2 infection resulting in PMWS associated with PNES. The lesions of PNES were initially observed at the same period (4-8 weeks of age) with the higher seroprevalence of PCV2 infection. Metaphylaxis of this case included intramuscular injection of florfenicol for the treatment and control of skin lesions and respiratory signs. Moreover, piglets were vaccinated against PCV2. In conclusion, sub-acute PCV2 infection could be included in triggering factors PNES in weaners. The mass vaccination against PCV2 of infected piglets might be effective in reduction of clinical signs and losses of PNES in cases of PCV2 infection associated with PNES.
猪坏死性耳综合征(PNES)在许多集约化养猪的国家已被报道为一个日益严重的健康问题。这种疾病的病因复杂,推测的触发因素可分为传染性和非传染性因素。本报告描述了一例2型猪圆环病毒(PCV2)感染病例,该感染与一个从仔猪到育肥猪的猪场断奶阶段的PNES病变有关。大约35%的断奶仔猪(断奶后1 - 3周)出现了类似于断奶后多系统消瘦综合征(PMWS)的临床症状。断奶后约2 - 3周,约20%的猪出现了PNES的最初病变,导致了一个严重的健康问题,其特征为生长不良或严重消瘦,最终某些批次的死亡率高达15%。此外,大约5%存活的断奶仔猪在生长/育肥阶段出现生长不良和继发性混合感染,导致死亡。基于临床症状、血清学和病理学检查的本研究表明,断奶仔猪遭受亚急性PCV2感染,导致与PNES相关的PMWS。PNES的病变最初在同一时期(4 - 8周龄)被观察到,此时PCV2感染的血清阳性率较高。该病例的预防性治疗包括肌肉注射氟苯尼考以治疗和控制皮肤病变及呼吸道症状。此外,给仔猪接种了PCV2疫苗。总之,亚急性PCV2感染可能是断奶仔猪PNES的触发因素之一。对感染仔猪大规模接种PCV2疫苗可能有效地减少与PNES相关的PCV2感染病例中的临床症状和PNES造成的损失。