应激、氧化损伤与疾病。
Stress, oxidative injury and disease.
作者信息
Srivastava Kaushal K, Kumar Ratan
机构信息
Indian National Academy of Stress Sciences, New Delhi, 110054 India.
出版信息
Indian J Clin Biochem. 2015 Jan;30(1):3-10. doi: 10.1007/s12291-014-0441-5. Epub 2014 Jun 1.
Abstract
The living system on earth is largely using oxygen for burning metabolic fuel for energy. The toxicity of oxygen is largely due to the formation of free radicals in living systems. Stress is also responsible for the generation of free radicals. The evidence for the involvement of free radicals and oxidative injury in producing metabolic disturbance, maladjustment and many diseases has been accumulating since long. It is largely believed that the root cause of many chronic diseases is stress induced free radicals and resultant oxidative injury.
摘要
地球上的生命系统主要利用氧气燃烧代谢燃料来获取能量。氧气的毒性很大程度上是由于生命系统中自由基的形成。压力也是自由基产生的原因。长期以来，自由基和氧化损伤参与产生代谢紊乱、适应不良和许多疾病的证据一直在不断积累。人们普遍认为，许多慢性疾病的根本原因是压力诱导的自由基和由此产生的氧化损伤。
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