Gao Peng, Jiang Dapeng, Liu Wenjuan, Li Huaining, Li Zhaozhu
Department of pediatric surgery, the 2nd affiliated hospital of Harbin Medical University, Harbin, China.
Curr Stem Cell Res Ther. 2016;11(7):547-53. doi: 10.2174/1574888x10666150220161506.
Tissue engineering, as a frontier of medicine, is aimed at regeneration of tissue and organ which can be used for the therapy of many diseases, such as trauma, cancer, and deformity. Some pluripotent stem cells are considered to be suitable for seed cells for tissue engineering, for example, bone marrow mesenchymal stem cells, adipose-derived stem cells and epidermal stem cells. Urine-derived stem cells (USCs) have been reported, and regarded as a candidate for seed cells in tissue engineering because of low-cost collection and isolation, efficient proliferation, and multidifferentiation potential, which have been documented in recent years. In this paper, we will introduce the biological characteristics of USCs and their potential applications in tissue engineering.
组织工程作为医学前沿领域，旨在实现组织和器官的再生，可用于治疗多种疾病，如创伤、癌症和畸形。一些多能干细胞被认为适合作为组织工程的种子细胞，例如骨髓间充质干细胞、脂肪来源干细胞和表皮干细胞。尿源干细胞（USCs）已被报道，因其采集和分离成本低、增殖效率高以及具有多向分化潜能，近年来被视为组织工程种子细胞的候选者。在本文中，我们将介绍尿源干细胞的生物学特性及其在组织工程中的潜在应用。
