门静脉海绵样变相关性胆管病——临床特征
Portal cavernoma cholangiopathy-clinical characteristics.
作者信息
Duseja Ajay
机构信息
Department of Hepatology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
出版信息
J Clin Exp Hepatol. 2014 Feb;4(Suppl 1):S34-6. doi: 10.1016/j.jceh.2013.05.014. Epub 2013 Oct 22.
Abstract
Because of the presence of portal cavernoma, paracholedochal and pericholedochal varices, portal cavernoma cholangiopathy (PCC) has become an entity unique to patients with extrahepatic portal venous obstruction (EHPVO). Majority of patients with these abnormalities are asymptomatic and are incidentally detected to have the presence of biliary abnormalities on cholangiography. Minority of patients present with symptoms of chronic cholestasis with or without biliary pain or acute cholangitis related most often to the presence of biliary strictures or stones. Other than the age of the patient and duration of EHPVO, presence of gall stones and common bile duct stones are other risk factors for the causation of symptoms in patients with PCC. This review summarizes the clinical characteristics of asymptomatic and symptomatic patients with PCC giving details of the prevalence of symptoms, their risk factors and overall burden of symptomatic PCC.
摘要
由于存在门静脉海绵样变性、胆管旁和胆管周围静脉曲张，门静脉海绵样变性胆管病（PCC）已成为肝外门静脉阻塞（EHPVO）患者所特有的一种病症。大多数有这些异常情况的患者没有症状，是在胆管造影时偶然发现有胆道异常。少数患者出现慢性胆汁淤积症状，伴有或不伴有胆绞痛，或急性胆管炎，这最常与胆道狭窄或结石的存在有关。除了患者年龄和EHPVO的病程外，胆结石和胆总管结石的存在是PCC患者出现症状的其他危险因素。本综述总结了无症状和有症状PCC患者的临床特征，详细介绍了症状的发生率、危险因素以及有症状PCC的总体负担。
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