纯干扰素对体外爱泼斯坦-巴尔病毒感染的影响。
Effects of pure interferons on Epstein-Barr virus infection in vitro.
作者信息
Andersson J P, Andersson U G, Ernberg I T, Britton S F, DeLey M
出版信息
J Virol. 1985 May;54(2):615-8. doi: 10.1128/JVI.54.2.615-618.1985.
Abstract
Pure human gamma-interferon as well as alpha-interferon inhibited induction of immunoglobulin synthesis by Epstein-Barr virus but not by pokeweed mitogen in B lymphocytes from adult but not from newborn humans. The interferons inhibited the infected B lymphocytes directly, irrespective of the Epstein-Barr virus immune status of the donor, and their inhibitory effect was synergistic.
摘要
纯人γ干扰素以及α干扰素可抑制爱泼斯坦-巴尔病毒诱导成人而非新生儿B淋巴细胞合成免疫球蛋白，但对商陆有丝分裂原诱导的免疫球蛋白合成无抑制作用。干扰素直接抑制受感染的B淋巴细胞，与供体的爱泼斯坦-巴尔病毒免疫状态无关，且其抑制作用具有协同性。
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