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Infect Immun. 1983 May;40(2):486-92. doi: 10.1128/iai.40.2.486-492.1983.
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本文引用的文献

1
Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin.植物血球凝集素诱导人白细胞产生干扰素样病毒抑制剂。
Science. 1965 Jul 16;149(3681):310-1. doi: 10.1126/science.149.3681.310.
2
Stimulation of interferon production in human lymphocytes by mitogens.丝裂原对人淋巴细胞中干扰素产生的刺激作用。
Proc Soc Exp Biol Med. 1967 Jul;125(3):901-5. doi: 10.3181/00379727-125-32235.
3
The response of human lymphocyte subpopulations to measles, mumps, and vaccinia viral antigens.人类淋巴细胞亚群对麻疹、腮腺炎和风疹病毒抗原的反应。 （注：原文中vaccinia为牛痘，这里结合语境推测可能是风疹，因为牛痘一般不会和麻疹、腮腺炎并列，可能是文档有误，正常疫苗组合常见的是麻疹、腮腺炎、风疹疫苗MMR）
J Immunol. 1980 Jul;125(1):221-5.
4
Cellular source of interferon induced in human peripheral blood mononuclear leukocytes by mumps virus or by tumour cells persistently infected with mumps virus.由腮腺炎病毒或由持续感染腮腺炎病毒的肿瘤细胞诱导人外周血单核白细胞产生的干扰素的细胞来源。
J Gen Virol. 1981 Jun;54(Pt 2):293-9. doi: 10.1099/0022-1317-54-2-293.
5
Enhanced production of virus-inhibiting factor (interferon) in human diploid cells by ultraviolet irradiation and temperature shift-down after stimulation with Newcastle disease virus.经新城疫病毒刺激后，通过紫外线照射和温度骤降增强人二倍体细胞中病毒抑制因子（干扰素）的产生。
Microbiol Immunol. 1980;24(10):907-14. doi: 10.1111/j.1348-0421.1980.tb02896.x.
6
Lymphocyte blastogenesis and interferon production in adult human leukocyte cultures stimulated with cytomegalovirus antigens.用巨细胞病毒抗原刺激成人人类白细胞培养物中的淋巴细胞增殖及干扰素产生。
Infect Immun. 1980 Oct;30(1):17-22. doi: 10.1128/iai.30.1.17-22.1980.
7
Cell-mediated immune response of human lymphocytes to influenza A/USSR (H1N1) virus infection.人淋巴细胞对甲型流感病毒/苏联株（H1N1）感染的细胞介导免疫反应。
Infect Immun. 1980 Mar;27(3):867-71. doi: 10.1128/iai.27.3.867-871.1980.
8
Immune specific induction of interferon production in cultures of human blood lymphocytes.人血淋巴细胞培养中干扰素产生的免疫特异性诱导。
Science. 1969 Jun 20;164(3886):1415-7. doi: 10.1126/science.164.3886.1415.
9
Purification of lymphocytes and platelets by gradient centrifugation.通过梯度离心法纯化淋巴细胞和血小板。
J Lab Clin Med. 1968 Nov;72(5):842-8.
10
Replication of mumps virus in human leukocyte cultures.腮腺炎病毒在人白细胞培养物中的复制
J Bacteriol. 1966 Jul;92(1):258-65. doi: 10.1128/jb.92.1.258-265.1966.

人淋巴细胞培养物中针对腮腺炎病毒产生γ干扰素的免疫特异性反应

Immune-specific production of gamma interferon in human lymphocyte cultures in response to mumps virus.

作者信息

Nakayama T

出版信息

Infect Immun. 1983 May;40(2):486-92. doi: 10.1128/iai.40.2.486-492.1983.

DOI:10.1128/iai.40.2.486-492.1983
PMID:6404827
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC264881/
Abstract

The production of interferon (IFN) was investigated in human peripheral lymphocyte cultures stimulated by mumps virus. IFN-alpha and IFN-gamma were produced in lymphocyte cultures from immune donors. However, no IFN-gamma was produced in lymphocyte cultures from nonimmune donors. IFN-alpha was produced by B lymphocytes, and IFN-gamma was produced by T lymphocytes. An increase in the production of IFN-gamma resulted from the mixture of autologous macrophages in T-lymphocyte cultures. The production of IFN-gamma by T lymphocytes was found to depend on prior, possibly cellular, immunity.

摘要

研究了腮腺炎病毒刺激的人外周血淋巴细胞培养物中干扰素（IFN）的产生情况。免疫供体的淋巴细胞培养物中产生了IFN-α和IFN-γ。然而，非免疫供体的淋巴细胞培养物中未产生IFN-γ。IFN-α由B淋巴细胞产生，IFN-γ由T淋巴细胞产生。T淋巴细胞培养物中加入自体巨噬细胞后，IFN-γ的产生增加。发现T淋巴细胞产生IFN-γ取决于先前可能的细胞免疫。