Ben Nejma Aymen, Nguir Asma, Ben Jannet Hichem, Hamza M'hamed Ali, Daïch Adam, Othman Mohamed, Lawson Ata Martin
Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia.
Laboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11SE39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Avenue of Environment, 5019 Monastir, Tunisia.
Bioorg Med Chem Lett. 2015 Apr 15;25(8):1665-1670. doi: 10.1016/j.bmcl.2015.03.028. Epub 2015 Mar 18.
The phytochemical investigation of a Tunisian plant Atriplex portulacoides (Chenopodiaceae) led to the isolation of two new compounds designated as portulasoid (2) and septanoecdysone (3) along with the known 20-hydroxyecdysone (20HE) (1). Their chemical structures were elucidated on the basis of extensive spectroscopic methods including ES-HRMS, 1D and 2D-NMR. The isolated compounds were finally tested for their antioxidant activity by using DPPH, ABTS(+), Fe(3+) and catalase assays and also for their antibacterial and anticholinesterase activities.
对突尼斯植物海滨藜（藜科）进行的植物化学研究，分离出了两种新化合物，分别命名为海滨藜素（2）和七氢蜕皮激素（3），以及已知的20-羟基蜕皮激素（20HE）（1）。通过包括电喷雾高分辨质谱、一维和二维核磁共振在内的多种光谱方法阐明了它们的化学结构。最终，利用二苯基苦味酰基自由基（DPPH）、阳离子自由基ABTS(+)、铁离子（Fe(3+)）和过氧化氢酶检测法，对分离出的化合物的抗氧化活性进行了测试，还测试了它们的抗菌和抗胆碱酯酶活性。
