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瑞香狼毒叶和茎的水提取物、水醇提取物及醇提取物对口腔细菌生长的抗菌抑制活性。

Antimicrobial inhibitory activity of aqueous, hydroalcoholic and alcoholic extracts of leaves and stem of Daphne mucronata on growth of oral bacteria.

作者信息

Shirzadi Karamolah Kolsoom, Mousavi Fatemeh, Mahmoudi Hassan

机构信息

Islamic Azad University, Boroujerd Branch, Lorstan, Iran.

Microbiology Department, Hamadan University of Medical Sciences, Hamadān, Iran.

出版信息

GMS Hyg Infect Control. 2017 Oct 2;12:Doc16. doi: 10.3205/dgkh000301. eCollection 2017.

DOI:10.3205/dgkh000301
PMID:28989855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5627145/
Abstract

Plants are a source of potential anti-infective agents. is a shrub in the family Thymelaeaceae, which has therapeutic effects. The aim of the present study was to evaluate the antimicrobial activity of aqueous, hydroalcoholic and alcoholic extracts of the leaves and stem of on the growth of oral bacteria. Leaves and stem of were collected from the Zagros Mountains, Lorestan, Iran. They were air dried in the shade. Aqueous, hydroalcoholic and alcoholic extracts of were made by using classic techniques for solvent extraction of plant material. The antimicrobial effects of the extracts were evaluated using the agar disk diffusion method (ADDM) and the minimum inhibitory concentration (MIC). The data were analyzed using Duncan's test and ANOVA. The results showed that the antimicrobial activity depended on the type of extract. The alcoholic extract of had the highest antibacterial activity and the highest effect on . The aqueous extract of the plant had no effect on bacterial growth. On the basis of the current results, the alcoholic extract of might be promising as a natural antimicrobial agent and as a medicine for the prevention and control of the growth of .

摘要

植物是潜在抗感染剂的来源。[植物名称]是瑞香科的一种灌木,具有治疗作用。本研究的目的是评估[植物名称]叶和茎的水提取物、水醇提取物和醇提取物对口腔细菌生长的抗菌活性。[植物名称]的叶和茎采自伊朗洛雷斯坦省的扎格罗斯山脉。它们在阴凉处风干。[植物名称]的水提取物、水醇提取物和醇提取物采用经典的植物材料溶剂萃取技术制备。使用琼脂平板扩散法(ADDM)和最低抑菌浓度(MIC)评估[植物名称]提取物的抗菌效果。数据采用邓肯检验和方差分析进行分析。结果表明,抗菌活性取决于提取物的类型。[植物名称]的醇提取物具有最高的抗菌活性,对[细菌名称]的影响最大。该植物的水提取物对细菌生长没有影响。基于目前的结果,[植物名称]的醇提取物有望作为一种天然抗菌剂以及预防和控制[细菌名称]生长的药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/20d9f4d06c89/HIC-12-16-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/2c31b22fccb2/HIC-12-16-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/5b43786fed01/HIC-12-16-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/20d9f4d06c89/HIC-12-16-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/2c31b22fccb2/HIC-12-16-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/5b43786fed01/HIC-12-16-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a278/5627145/20d9f4d06c89/HIC-12-16-t-003.jpg

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