Program in Barrier Immunity and Repair, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA; Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA.
Program in Barrier Immunity and Repair, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA; Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA.
Cell. 2015 Apr 9;161(2):193-4. doi: 10.1016/j.cell.2015.03.033.
Serotonin is a highly ubiquitous signaling molecule that plays a role in the regulation of various physiological functions. Several lines of evidence, including the present work from Hsiao and colleagues, demonstrate that, in the gut, microbial-derived metabolites affect the production of serotonin that in turn impacts host physiological functions.
血清素是一种高度普遍存在的信号分子,在调节各种生理功能中发挥作用。包括 Hsiao 及其同事的这项工作在内的几项证据表明,在肠道中,微生物衍生的代谢物会影响血清素的产生,而血清素反过来又会影响宿主的生理功能。