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含有南美酒神菊提取物的草本漱口水作为生物膜控制剂:人体临床评估

Herbal mouthwash containing extracts of Baccharis dracunculifolia as agent for the control of biofilm: clinical evaluation in humans.

作者信息

Pedrazzi Vinícius, Leite Mateus Freire, Tavares Reisla Cristina, Sato Sandra, do Nascimento Glauce Crivelaro, Issa João Paulo Mardegan

机构信息

Department of Dental Materials and Prosthodontics, Ribeirão Preto Dentistry Faculty, University of São Paulo, 14040-904 Ribeirão Preto, SP, Brazil.

Multidisciplinary Institute for Health, Federal University of Bahia, Anísio Teixeira Campus, 45029-094 Vitoria da Conquista, BA, Brazil.

出版信息

ScientificWorldJournal. 2015;2015:712683. doi: 10.1155/2015/712683. Epub 2015 Mar 22.

DOI:10.1155/2015/712683
PMID:25874255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4385682/
Abstract

Baccharis dracunculifolia DC (Asteraceae), popularly known as "alecrim-do-campo," is largely distributed in South America, is shown to exhibit protective actions against gastric ulcers, has anti-inflammatory properties, and is hepatoprotective. Several essential oils obtained from Baccharis species possess biological activities, such as antimicrobial and antivirus activities. This randomized controlled trial evaluated the efficacy of B. dracunculifolia in the reduction of dental biofilm, comparing this natural product with other mouthwashes already known in the dental market. In measuring the time after use of mouthwash (t = 1), there was no difference between products (P = 0.602); that is, subjects in the study had a similar PI after the first use. After one week (t = 2), there was no difference between the four products evaluated (P = 0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). It is possible to conclude that B. dracunculifolia had the same efficiency of the materials used to oral hygiene in reduction of dental plaque and, consequently, prevention of dental caries. Thus, we can consider B. dracunculifolia as a good candidate for new material to be implemented in dental care.

摘要

地胆草(菊科),俗称“田野百里香”,广泛分布于南美洲,具有抗胃溃疡、抗炎和保肝作用。从地胆草属植物中提取的几种精油具有生物活性,如抗菌和抗病毒活性。这项随机对照试验评估了地胆草在减少牙菌斑方面的功效,并将这种天然产品与牙科市场上已知的其他漱口水进行了比较。在测量使用漱口水后的时间(t = 1)时,各产品之间没有差异(P = 0.602);也就是说,研究中的受试者在首次使用后菌斑指数相似。一周后(t = 2),评估的四种产品之间没有差异(P = 0.674),因此,所有研究对象在完成研究时牙菌斑减少程度相似,但与初始状态不同(弗里德曼检验)。可以得出结论,地胆草在减少牙菌斑从而预防龋齿方面与用于口腔卫生的材料具有相同的效果。因此,我们可以将地胆草视为牙科护理中新材料的良好候选者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1048/4385682/918c7f4c12f2/TSWJ2015-712683.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1048/4385682/918c7f4c12f2/TSWJ2015-712683.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1048/4385682/918c7f4c12f2/TSWJ2015-712683.001.jpg

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