圣罗勒和姜黄在口腔黏膜下纤维化治疗中作用的临床评估：一项前瞻性初步观察研究。
Clinical evaluation of the role of tulsi and turmeric in the management of oral submucous fibrosis: A pilot, prospective observational study.
作者信息
Srivastava Adit, Agarwal Rahul, Chaturvedi T P, Chandra Akhilesh, Singh O P
机构信息
Department of Oral Medicine and Radiology, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
出版信息
J Ayurveda Integr Med. 2015 Jan-Mar;6(1):45-9. doi: 10.4103/0975-9476.146563.
The aim of the present study was to investigate the clinical efficacy of herbal medicines (1 gm tulsi and 1 gm turmeric mixed in glycerine base) for the treatment of oral submucous fibrosis (OSMF). Forty-one patients in the age group of 17- 56 years without any systemic complications were included in the study. The patients were treated with medicines, which were to be applied 3-4 times a day. Blood samples were collected before and after treatment to screen for any systemic changes due to these medications. Burning sensation and mouth opening were recorded before and after treatment. Patients were followed up on monthly subsequent visits for three months. Changes in the burning sensation on visual analogue scale (VAS) scale and difference in the mouth opening were analyzed statistically. A statistically significant improvement was seen in both burning sensation and mouth opening. Tulsi and turmeric offers a safe and efficacious combination of natural products available for symptomatic treatment of OSMF.
本研究的目的是调查草药（1克罗勒和1克姜黄混合于甘油基质中）治疗口腔黏膜下纤维化（OSMF）的临床疗效。研究纳入了41名年龄在17至56岁之间且无任何全身并发症的患者。患者接受药物治疗，药物每天应用3至4次。在治疗前后采集血样，以筛查这些药物引起的任何全身变化。记录治疗前后的烧灼感和张口度。患者在随后的三个月中每月随访一次。对视觉模拟量表（VAS）上烧灼感的变化和张口度的差异进行统计学分析。在烧灼感和张口度方面均观察到具有统计学意义的改善。罗勒和姜黄提供了一种安全有效的天然产物组合，可用于OSMF的对症治疗。
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