Özcura Fatih, Yildirim Nilgün, Şahin Afsun, Çolak Ertuğrul
Department of Ophthalmology, Dumlupinar University School of Medicine, Kutahya 43270, Turkey.
Department of Ophthalmology, Eskisehir Osmangazi University School of Medicine, Eskisehir 26480, Turkey.
Int J Ophthalmol. 2015 Apr 18;8(2):299-304. doi: 10.3980/j.issn.2222-3959.2015.02.15. eCollection 2015.
To compare the intraocular pressure (IOP) measurements obtained with the rebound tonometry (RT), dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) in normal and glaucomatous eyes and investigate the effects of central corneal thickness (CCT) and corneal curvature (CC) on IOP measurements.
One hundred and twenty-four eyes of 124 subjects were enrolled in this cross-sectional study. Fifty-six of participants were healthy individuals and 68 of them were glaucomatous patients. IOP was measured on each subject always in the same order, ICare RT-Pascal DCT-GAT, after a minimum interval of 10min between measurements. CCT and CC were measured using a rotating Scheimpflug camera before the IOP measurements in all subjects. One way repeated measures ANOVA, Pearson correlation coefficient and regression analysis, and Bland-Altman analysis was used for the statistical assessment.
Mean IOP for all enrolled eyes was 16.00±3.80 mm Hg for GAT, 16.99±4.91 mm Hg for RT, and 20.40±4.44 mm Hg for DCT. Mean differences between GAT and RT was -1.75±3.41 mm Hg in normal (P<0.001) and -0.37±3.00 mm Hg in glaucomatous eyes (P=0.563). Mean differences between GAT and DCT was -4.06±3.42 mm Hg in normal (P<0.001) and -4.67±3.12 mm Hg in glaucomatous eyes (P<0.001). GAT and RT were significantly positive correlated with CCT in normal (r=0.317, P=0.017 and r=0.576, P<0.001, respectively) and glaucomatous eyes (r=0.290, P=0.016 and r=0.351, P=0.003, respectively). DCT was also significantly positive correlated with CCT in normal eyes (r=0.424, P=0.001) but not in glaucomatous eyes (r=0.170, P=0.165). All tonometers were unaffected by CC.
IOP measurements by RT and DCT were significantly higher than GAT. DCT has highest IOP measurements among these tonometers. RT was most influenced tonometer from CCT although all tonometers were significantly positive correlated with CCT except DCT in glaucomatous eyes. CC did not influence IOP measurements.
比较正常眼和青光眼眼中使用回弹式眼压计（RT）、动态轮廓眼压计（DCT）和Goldmann压平眼压计（GAT）测量的眼压（IOP），并研究中央角膜厚度（CCT）和角膜曲率（CC）对眼压测量的影响。
本横断面研究纳入了124名受试者的124只眼睛。56名参与者为健康个体，68名为青光眼患者。每次测量前至少间隔10分钟，按照ICare RT-Pascal DCT-GAT的顺序对每位受试者测量眼压。在所有受试者测量眼压之前，使用旋转式Scheimpflug相机测量CCT和CC。采用单因素重复测量方差分析、Pearson相关系数和回归分析以及Bland-Altman分析进行统计学评估。
所有纳入眼睛的平均眼压，GAT为16.00±3.80 mmHg，RT为16.99±4.91 mmHg，DCT为20.40±4.44 mmHg。GAT与RT在正常眼中的平均差值为-1.75±3.41 mmHg（P<0.001），在青光眼眼中为-0.37±3.00 mmHg（P=0.563）。GAT与DCT在正常眼中的平均差值为-4.06±3.42 mmHg（P<0.001），在青光眼眼中为-4.67±3.12 mmHg（P<0.001）。GAT和RT在正常眼（分别为r=0.317，P=0.017和r=0.576，P<0.001）和青光眼眼中（分别为r=0.290，P=0.016和r=0.351，P=0.003）与CCT均显著正相关。DCT在正常眼中也与CCT显著正相关（r=0.424，P=0.001），但在青光眼眼中无相关性（r=0.170，P=0.165）。所有眼压计均不受CC影响。
RT和DCT测量的眼压显著高于GAT。这些眼压计中DCT测量的眼压最高。RT受CCT影响最大，尽管除青光眼眼中的DCT外，所有眼压计与CCT均显著正相关。CC不影响眼压测量。
