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不完美世界中的疫情预测:利用部分数据对疾病传播进行建模

Epidemic predictions in an imperfect world: modelling disease spread with partial data.

作者信息

Dawson Peter M, Werkman Marleen, Brooks-Pollock Ellen, Tildesley Michael J

机构信息

Centre for Complexity Science, University of Warwick, Coventry CV4 7AL, UK

School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington LE12 5RD, UK Central Veterinary Institute, Wageningen UR (CVI), PO Box 65, 8200 AB Lelystad, The Netherlands.

出版信息

Proc Biol Sci. 2015 Jun 7;282(1808):20150205. doi: 10.1098/rspb.2015.0205.

Abstract

'Big-data' epidemic models are being increasingly used to influence government policy to help with control and eradication of infectious diseases. In the case of livestock, detailed movement records have been used to parametrize realistic transmission models. While livestock movement data are readily available in the UK and other countries in the EU, in many countries around the world, such detailed data are not available. By using a comprehensive database of the UK cattle trade network, we implement various sampling strategies to determine the quantity of network data required to give accurate epidemiological predictions. It is found that by targeting nodes with the highest number of movements, accurate predictions on the size and spatial spread of epidemics can be made. This work has implications for countries such as the USA, where access to data is limited, and developing countries that may lack the resources to collect a full dataset on livestock movements.

摘要

“大数据”疫情模型正越来越多地被用于影响政府政策,以帮助控制和根除传染病。就牲畜而言,详细的移动记录已被用于为现实的传播模型设定参数。虽然英国和欧盟其他国家有现成的牲畜移动数据,但在世界上许多国家,此类详细数据并不存在。通过使用英国牛贸易网络的综合数据库,我们实施了各种抽样策略,以确定给出准确流行病学预测所需的网络数据量。研究发现,通过针对移动次数最多的节点,能够对疫情的规模和空间传播做出准确预测。这项工作对数据获取受限的美国等国家以及可能缺乏资源来收集牲畜移动完整数据集的发展中国家具有启示意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2c87/4455802/560bec333d14/rspb20150205-g1.jpg

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