Dandona L, Quigley H A, Jampel H D
Wilmer Ophthalmological Institute, Johns Hopkins University, School of Medicine, Baltimore, Md 21205.
Arch Ophthalmol. 1989 Dec;107(12):1786-92. doi: 10.1001/archopht.1989.01070020868029.
Computerized topographic mapping of 10 repeated fundus images of one eye each in 10 healthy subjects and in 10 subjects with elevated intraocular pressures (IOPs) was performed with the Humphrey Retinal Analyzer. The variability of depth measurements at 400 to 650 individual locations in the optic nerve head and peripapillary retina was evaluated. The average size of the 95% confidence intervals for individual depth measurements for healthy subjects and those with elevated IOPs were 166 and 232 microns in the optic nerve head and 205 and 261 microns in the peripapillary retina, respectively. Variability was significantly less for healthy subjects than for those with elevated IOPs. Variability was significantly greater for depth measurements in the peripapillary retina than for measurements in the optic head. Knowledge about variability of individual depth measurements is useful for proper interpretation of computerized topographic mapping to detect retinal nerve fiber damage.
使用汉弗莱视网膜分析仪对10名健康受试者和10名眼压升高受试者的每只眼睛的10张重复眼底图像进行计算机地形图绘制。评估了视神经乳头和视乳头周围视网膜中400至650个单独位置的深度测量值的变异性。健康受试者和眼压升高受试者个体深度测量的95%置信区间的平均大小，在视神经乳头分别为166微米和232微米，在视乳头周围视网膜分别为205微米和261微米。健康受试者的变异性明显小于眼压升高的受试者。视乳头周围视网膜深度测量的变异性明显大于视神经乳头测量的变异性。了解个体深度测量的变异性有助于正确解读计算机地形图以检测视网膜神经纤维损伤。
