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荷兰不同文化背景的儿童和青少年在注意力缺陷多动障碍(ADHD)药物使用模式上的差异。

Differences in ADHD medication usage patterns in children and adolescents from different cultural backgrounds in the Netherlands.

作者信息

van den Ban Els F, Souverein Patrick C, van Engeland Herman, Swaab Hanna, Egberts Toine C G, Heerdink Eibert R

机构信息

Youth Division Altrecht, Institute for Mental Health, Nieuwe Houtenseweg 2, 3524 SH, Utrecht, The Netherlands,

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2015 Jul;50(7):1153-62. doi: 10.1007/s00127-015-1068-4. Epub 2015 May 28.

Abstract

PURPOSE

Differences in incidence and prevalence of ADHD medication use between ethnic groups have been reported. Goal of this study was to determine whether there are also differences in usage patterns of ADHD medication among native Dutch children and adolescents and those with a Moroccan, Turkish and Surinam cultural background in the Netherlands between 1999 and 2010.

METHODS

In a cohort of ADHD patients <19 years (N = 817) incident use and discontinuation of ADHD medication were measured for ethnicity and adjusted for age, gender and socio-economic status.

RESULTS

A significant higher proportion of ADHD-diagnosed patients from Moroccan (32 %) and Turkish (42 %) cultural background never used ADHD medication compared to Dutch natives (21 %). One-fifth of native Dutch and Turkish patients already used ADHD medication before the ADHD diagnosis date. Discontinuation of ADHD medication within 5 years was significantly higher in Moroccan [HR 2.4 (95 % CI 1.8-3.1)] and Turkish [HR 1.7 (95 % CI 1.1-2.6)] patients. A sensitivity analysis with a zip code-matched comparison between Dutch natives and non-natives showed similar results, suggesting this effect is probably not explained by socio-economic status (SES).

CONCLUSION

Differences are found in prescribing and use of ADHD medication between patients with a different cultural background. Native Dutch and Turkish patients start more frequently with ADHD medication before the ADHD diagnose date, which can be an indication of differences in either referral patterns and/or access to care. A higher percentage of patients with a Moroccan and Turkish cultural background never start using ADHD medication at all and discontinuation rate is higher compared to Dutch natives and Surinamese.

摘要

目的

已有报道称不同种族群体在多动症药物使用的发病率和流行率上存在差异。本研究的目的是确定1999年至2010年间,在荷兰本土儿童和青少年以及具有摩洛哥、土耳其和苏里南文化背景的儿童和青少年中,多动症药物的使用模式是否也存在差异。

方法

在一个年龄小于19岁的多动症患者队列(N = 817)中,对多动症药物的首次使用和停药情况按种族进行了测量,并对年龄、性别和社会经济地位进行了调整。

结果

与荷兰本土人(21%)相比,来自摩洛哥(32%)和土耳其(42%)文化背景的多动症确诊患者中,从未使用过多动症药物的比例显著更高。五分之一的荷兰本土和土耳其患者在多动症诊断日期之前就已经开始使用多动症药物。摩洛哥患者[风险比(HR)2.4(95%置信区间1.8 - 3.1)]和土耳其患者[HR 1.7(95%置信区间1.1 - 2.6)]在5年内停用多动症药物的比例显著更高。一项对荷兰本土人和非本土人进行邮政编码匹配比较的敏感性分析显示了类似的结果,表明这种效应可能无法用社会经济地位(SES)来解释。

结论

不同文化背景的患者在多动症药物的处方和使用上存在差异。荷兰本土和土耳其患者在多动症诊断日期之前更频繁地开始使用多动症药物,这可能表明在转诊模式和/或获得医疗服务方面存在差异。与荷兰本土人和苏里南人相比,具有摩洛哥和土耳其文化背景的患者中,从未开始使用多动症药物的比例更高,停药率也更高。

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