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用于绿色合成纳米银的生物纳米工厂:迈向抗菌应用。

Bionanofactories for Green Synthesis of Silver Nanoparticles: Toward Antimicrobial Applications.

机构信息

Department of Pharmaceutical Sciences & Technology, Institute of Chemical Technology, Nathalal Parekh Marg, Matunga, Mumbai 400019, India.

Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.

出版信息

Int J Mol Sci. 2021 Nov 5;22(21):11993. doi: 10.3390/ijms222111993.

Abstract

Among the various types of nanoparticles and their strategy for synthesis, the green synthesis of silver nanoparticles has gained much attention in the biomedical, cellular imaging, cosmetics, drug delivery, food, and agrochemical industries due to their unique physicochemical and biological properties. The green synthesis strategies incorporate the use of plant extracts, living organisms, or biomolecules as bioreducing and biocapping agents, also known as bionanofactories for the synthesis of nanoparticles. The use of green chemistry is ecofriendly, biocompatible, nontoxic, and cost-effective. We shed light on the recent advances in green synthesis and physicochemical properties of green silver nanoparticles by considering the outcomes from recent studies applying SEM, TEM, AFM, UV/Vis spectrophotometry, FTIR, and XRD techniques. Furthermore, we cover the antibacterial, antifungal, and antiparasitic activities of silver nanoparticles.

摘要

在各种类型的纳米粒子及其合成策略中,由于其独特的物理化学和生物学特性,绿色合成银纳米粒子在生物医学、细胞成像、化妆品、药物输送、食品和农用化学品等领域引起了广泛关注。绿色合成策略包括使用植物提取物、生物体或生物分子作为生物还原剂和生物封端剂,也称为纳米工厂,用于合成纳米粒子。绿色化学的使用具有环保、生物相容、无毒和具有成本效益的特点。我们通过考虑应用 SEM、TEM、AFM、UV/Vis 分光光度法、FTIR 和 XRD 技术的最新研究结果,介绍了绿色合成和绿色银纳米粒子的物理化学性质的最新进展。此外,我们还介绍了银纳米粒子的抗菌、抗真菌和抗寄生虫活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7079/8584914/2bebab747a48/ijms-22-11993-g001.jpg

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