Kocatürk Tolga, Bekmez Sinan, Katrancı Merve, Çakmak Harun, Dayanır Volkan
Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey.
Department of Biostatistics, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey.
Open Ophthalmol J. 2015 Jun 26;9:116-20. doi: 10.2174/1874364101509010116. eCollection 2015.
To evaluate visual field progression with trend and event analysis in open angle glaucoma patients under treatment.
Fifteen year follow-up results of 408 eyes of 217 glaucoma patients who were followed at Adnan Menderes University, Department of Ophthalmology between 1998 and 2013 were analyzed retrospectively. Visual field data were collected for Mean Deviation (MD), Visual Field Index (VFI), and event occurrence.
There were 146 primary open-angle glaucoma (POAG), 123 pseudoexfoliative glaucoma (XFG) and 139 normal tension glaucoma (NTG) eyes. MD showed significant change in all diagnostic groups (p<0.001). The difference of VFI between first and last examinations were significantly different in POAG (p<0.001), and XFG (p<0.003) but not in NTG. VFI progression rates were -0.3, -0.43, and -0.2 % loss/year in treated POAG, XFG, and NTG, respectively. The number of empty triangles were statistically different between POAG-NTG (p=0.001), and XFG-NTG (p=0.002) groups. The number of half-filled (p=0.002), and full-filled (p=0.010) triangles were significantly different between XFG-NTG groups.
Functional long-term follow-up of glaucoma patients can be monitored with visual field indices. We herein report our fifteen year follow-up results in open angle glaucoma.
通过趋势分析和事件分析评估接受治疗的开角型青光眼患者的视野进展情况。
回顾性分析了1998年至2013年间在阿德南·门德雷斯大学眼科随访的217例青光眼患者408只眼的15年随访结果。收集了平均偏差（MD）、视野指数（VFI）和事件发生情况的视野数据。
有146只原发性开角型青光眼（POAG）眼、123只剥脱性青光眼（XFG）眼和139只正常眼压性青光眼（NTG）眼。MD在所有诊断组中均显示出显著变化（p<0.001）。POAG组（p<0.001）和XFG组（p<0.003）首次和末次检查之间的VFI差异有统计学意义，但NTG组无差异。接受治疗的POAG、XFG和NTG组的VFI进展率分别为每年损失-0.3%、-0.43%和-0.2%。POAG-NTG组（p=0.001）和XFG-NTG组（p=0.002）之间空三角的数量有统计学差异。XFG-NTG组之间半填充（p=0.002）和全填充（p=0.010）三角的数量有显著差异。
青光眼患者的功能性长期随访可以通过视野指数进行监测。本文报告了我们对开角型青光眼的15年随访结果。
