Dawidowicz Joanna, Szotek Sylwia, Matysiak Natalia, Mielańczyk Łukasz, Maksymowicz Krzysztof
Veterinary Clinic "Brynów", Katowice, Poland.
Faculty of Mechanical Engineering, Wrocław University of Technology, Wrocław, Poland.
J Cell Mol Med. 2015 Oct;19(10):2500-6. doi: 10.1111/jcmm.12665. Epub 2015 Aug 27.
From the histological point of view, fascia lata is a dense connective tissue. Although extracellular matrix is certainly the most predominant fascia's feature, there are also several cell populations encountered within this structure. The aim of this study was to describe the existence and characteristics of fascia lata cell populations viewed through a transmission electron microscope. Special emphasis was placed on telocytes as a particular interstitial cell type, recently discovered in a wide variety of tissues and organs such as the heart, skeletal muscles, skin, gastrointestinal tract, uterus and urinary system. The conducted study confirmed the existence of a telocyte population in fascia lata samples. Those cells fulfil main morphological criteria of telocytes, namely, the presence of very long, thin cell processes (telopodes) extending from a relatively small cell body. Aside from telocytes, we have found fibroblasts, mast cells and cells with features of myofibroblastic differentiation. This is the first time it has been shown that telocytes exist in human fascia. Currently, the exact role of those cells within the fascia is unknown and definitely deserves further attention. One can speculate that fascia lata telocytes likewise telocytes in other organs may be involved in regeneration, homeostasis and intracellular signalling.
从组织学角度来看，阔筋膜是一种致密结缔组织。尽管细胞外基质无疑是筋膜最主要的特征，但在这种结构中也能发现几种细胞群体。本研究的目的是通过透射电子显微镜描述阔筋膜细胞群体的存在及特征。特别强调了作为一种特殊间质细胞类型的间充质细胞，最近在多种组织和器官中被发现，如心脏、骨骼肌、皮肤、胃肠道、子宫和泌尿系统。所进行的研究证实了阔筋膜样本中间充质细胞群体的存在。这些细胞符合间充质细胞的主要形态学标准，即存在从相对较小的细胞体伸出的非常长且细的细胞突起（telopodes）。除了间充质细胞，我们还发现了成纤维细胞、肥大细胞以及具有肌成纤维细胞分化特征的细胞。这是首次表明间充质细胞存在于人体筋膜中。目前，这些细胞在筋膜内的确切作用尚不清楚，绝对值得进一步关注。可以推测，阔筋膜间充质细胞与其他器官中的间充质细胞一样，可能参与再生、内环境稳定和细胞内信号传导。
