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Dendrimer nanocarriers drug action: perspective for neuronal pharmacology.

作者信息

Vidal Felipe, Guzman Leonardo

机构信息

Laboratory of Molecular Neurobiology, Department of Physiology, Faculty of Biological Sciences, University of Concepcion, Chile.

出版信息

Neural Regen Res. 2015 Jul;10(7):1029-31. doi: 10.4103/1673-5374.160063.

DOI:10.4103/1673-5374.160063
PMID:26330812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4541220/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/ae5774f36a31/NRR-10-1029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/950fb3a3261f/NRR-10-1029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/f1f77e8a7df9/NRR-10-1029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/ae5774f36a31/NRR-10-1029-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/950fb3a3261f/NRR-10-1029-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/f1f77e8a7df9/NRR-10-1029-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/ae5774f36a31/NRR-10-1029-g003.jpg

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2
Cell-penetrating and neurotargeting dendritic siRNA nanostructures.细胞穿透和神经靶向树枝状 siRNA 纳米结构。
Angew Chem Int Ed Engl. 2015 Feb 2;54(6):1946-9. doi: 10.1002/anie.201409803. Epub 2014 Dec 17.
3
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.自噬在阳离子 PAMAM 树枝状聚合物神经毒性中的作用。
聚酰胺胺树枝状大分子:胶质瘤治疗中的脑靶向给药系统
Polymers (Basel). 2024 Jul 15;16(14):2022. doi: 10.3390/polym16142022.
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Dendrimer Platforms for Targeted Doxorubicin Delivery-Physicochemical Properties in Context of Biological Responses.树状聚合物载药平台用于阿霉素靶向递送-生物学反应背景下的理化性质。
Int J Mol Sci. 2024 Jun 29;25(13):7201. doi: 10.3390/ijms25137201.
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Polymeric nanoparticles (PNPs) for oral delivery of insulin.用于胰岛素口服递送的聚合物纳米粒(PNPs)。
J Nanobiotechnology. 2024 Jan 3;22(1):1. doi: 10.1186/s12951-023-02253-y.
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