树枝状聚合物纳米载体的药物作用：神经药理学展望 - Suppr

Dendrimer nanocarriers drug action: perspective for neuronal pharmacology.

作者信息

Vidal Felipe, Guzman Leonardo

机构信息

Laboratory of Molecular Neurobiology, Department of Physiology, Faculty of Biological Sciences, University of Concepcion, Chile.

出版信息

Neural Regen Res. 2015 Jul;10(7):1029-31. doi: 10.4103/1673-5374.160063.

DOI:10.4103/1673-5374.160063

PMID:26330812

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4541220/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d601/4541220/950fb3a3261f/NRR-10-1029-g001.jpg

相似文献

Dendrimer nanocarriers drug action: perspective for neuronal pharmacology.

Neural Regen Res. 2015 Jul;10(7):1029-31. doi: 10.4103/1673-5374.160063.

Dendrimer-based nanocarriers: a versatile platform for drug delivery.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jan;9(1). doi: 10.1002/wnan.1409. Epub 2016 Apr 29.

Highly lipophilic pluronics-conjugated polyamidoamine dendrimer nanocarriers as potential delivery system for hydrophobic drugs.

Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 2):992-999. doi: 10.1016/j.msec.2016.03.073. Epub 2016 Mar 26.

Synthesis and characterization of poly(propylene imine)-dendrimer-grafted gold nanoparticles as nanocarriers of doxorubicin.

Colloids Surf B Biointerfaces. 2017 Jul 1;155:257-265. doi: 10.1016/j.colsurfb.2017.04.029. Epub 2017 Apr 13.

Effect of grafting ratio of poly(propylene imine) dendrimer onto gold nanoparticles on the properties of colloidal hybrids, their DOX loading and release behavior and cytotoxicity.

Colloids Surf B Biointerfaces. 2019 Jun 1;178:500-507. doi: 10.1016/j.colsurfb.2019.03.050. Epub 2019 Mar 23.

α-Tocopherol Succinate-Anchored PEGylated Poly(amidoamine) Dendrimer for the Delivery of Paclitaxel: Assessment of in Vitro and in Vivo Therapeutic Efficacy.

Mol Pharm. 2019 Apr 1;16(4):1541-1554. doi: 10.1021/acs.molpharmaceut.8b01232. Epub 2019 Mar 12.

Principal Physicochemical Methods Used to Characterize Dendrimer Molecule Complexes Used as Genetic Therapy Agents, Nanovaccines or Drug Carriers.

Curr Pharm Des. 2017 Aug 30;23(21):3076-3083. doi: 10.2174/1381612823666170220164535.

Transport of dendrimer nanocarriers through epithelial cells via the transcellular route.

J Control Release. 2004 Jun 18;97(2):259-67. doi: 10.1016/j.jconrel.2004.03.022.

Low systemic toxicity nanocarriers fabricated from heparin-mPEG and PAMAM dendrimers for controlled drug release.

Mater Sci Eng C Mater Biol Appl. 2018 Jan 1;82:291-298. doi: 10.1016/j.msec.2017.07.051. Epub 2017 Jul 31.

Combined use of nanocarriers and physical methods for percutaneous penetration enhancement.

Adv Drug Deliv Rev. 2018 Mar 1;127:58-84. doi: 10.1016/j.addr.2018.02.003. Epub 2018 Feb 6.

引用本文的文献

Nanotherapeutic Strategies for Overcoming the Blood-Brain Barrier: Applications in Disease Modeling and Drug Delivery.

ACS Omega. 2025 Jul 24;10(30):32606-32625. doi: 10.1021/acsomega.5c02206. eCollection 2025 Aug 5.

Synergistic Cancer Therapies Enhanced by Nanoparticles: Advancing Nanomedicine Through Multimodal Strategies.

Pharmaceutics. 2025 May 22;17(6):682. doi: 10.3390/pharmaceutics17060682.

Polyamidoamine Dendrimers: Brain-Targeted Drug Delivery Systems in Glioma Therapy.

Polymers (Basel). 2024 Jul 15;16(14):2022. doi: 10.3390/polym16142022.

Dendrimer Platforms for Targeted Doxorubicin Delivery-Physicochemical Properties in Context of Biological Responses.

Int J Mol Sci. 2024 Jun 29;25(13):7201. doi: 10.3390/ijms25137201.

Polymeric nanoparticles (PNPs) for oral delivery of insulin.

J Nanobiotechnology. 2024 Jan 3;22(1):1. doi: 10.1186/s12951-023-02253-y.

A Review on Increasing the Targeting of PAMAM as Carriers in Glioma Therapy.

Biomedicines. 2022 Oct 1;10(10):2455. doi: 10.3390/biomedicines10102455.

Self-assembling ferritin-dendrimer nanoparticles for targeted delivery of nucleic acids to myeloid leukemia cells.

J Nanobiotechnology. 2021 Jun 9;19(1):172. doi: 10.1186/s12951-021-00921-5.

Developments in Treatment Methodologies Using Dendrimers for Infectious Diseases.

Molecules. 2021 May 31;26(11):3304. doi: 10.3390/molecules26113304.

A novel approach to label bone marrow-derived mesenchymal stem cells with mixed-surface PAMAM dendrimers.

Stem Cell Res Ther. 2019 Feb 28;10(1):71. doi: 10.1186/s13287-019-1171-7.

Use of Polyamidoamine Dendrimers in Brain Diseases.

Molecules. 2018 Sep 3;23(9):2238. doi: 10.3390/molecules23092238.

本文引用的文献

A holistic approach to targeting disease with polymeric nanoparticles.

Nat Rev Drug Discov. 2015 Apr;14(4):239-47. doi: 10.1038/nrd4503. Epub 2015 Jan 19.

Cell-penetrating and neurotargeting dendritic siRNA nanostructures.

Angew Chem Int Ed Engl. 2015 Feb 2;54(6):1946-9. doi: 10.1002/anie.201409803. Epub 2014 Dec 17.

The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.

Biomaterials. 2014 Aug;35(26):7588-97. doi: 10.1016/j.biomaterials.2014.05.029. Epub 2014 Jun 4.

Dendrimer advances for the central nervous system delivery of therapeutics.

ACS Chem Neurosci. 2014 Jan 15;5(1):2-13. doi: 10.1021/cn400182z. Epub 2013 Dec 5.

Nanotherapeutic approaches for brain cancer management.

Nanomedicine. 2014 Jul;10(5):905-19. doi: 10.1016/j.nano.2013.10.001. Epub 2013 Oct 14.

Sodium selective ion channel formation in living cell membranes by polyamidoamine dendrimer.

Biochim Biophys Acta. 2013 Aug;1828(8):1873-80. doi: 10.1016/j.bbamem.2013.04.004. Epub 2013 Apr 15.

Polyamidoamine dendrimer impairs mitochondrial oxidation in brain tissue.

J Nanobiotechnology. 2013 Apr 4;11:9. doi: 10.1186/1477-3155-11-9.

Modified PAMAM dendrimer with 4-carbomethoxypyrrolidone surface groups reveals negligible toxicity against three rodent cell-lines.

Nanomedicine. 2013 May;9(4):461-4. doi: 10.1016/j.nano.2013.01.010. Epub 2013 Feb 19.

Gene and doxorubicin co-delivery system for targeting therapy of glioma.

Biomaterials. 2012 Jun;33(19):4907-16. doi: 10.1016/j.biomaterials.2012.03.031. Epub 2012 Apr 7.

Dendrimer internalization and intracellular trafficking in living cells.

Mol Pharm. 2010 Jun 7;7(3):680-8. doi: 10.1021/mp9002464.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Dendrimer nanocarriers drug action: perspective for neuronal pharmacology.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

相似文献

引用本文的文献

本文引用的文献