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面部过敏性接触性皮炎患者的危险因素及常见接触性变应原

Risk factors and common contact allergens in facial allergic contact dermatitis patients.

作者信息

Kasemsarn Pranee, Iamphonrat Thanawan, Boonchai Waranya

机构信息

Contact Dermatitis Clinic, Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Int J Dermatol. 2016 Apr;55(4):417-24. doi: 10.1111/ijd.12880. Epub 2015 Sep 4.

Abstract

BACKGROUND

Facial dermatitis is commonly encountered in dermatologic practice. It is sometimes difficult to manage because its causative factors may be multiple and difficult to diagnose.

OBJECTIVES

This study was designed to identify the characteristics, patch test results, and final diagnoses of facial dermatitis patients who were referred to a contact dermatitis clinic and to identify factors associated with facial allergic contact dermatitis (ACD).

METHODS

We retrospectively reviewed case records of facial dermatitis patients who underwent patch testing at the clinic during the period from July 2006 to June 2011.

RESULTS

Of the 891 patients patch-tested, 244 (27.4%) had facial dermatitis. Female patients were 9.1 times more predominant than male patients. The mean ± standard deviation age of patients was 37.3 ± 14.8 years. A total of 199 (81.6%) patients demonstrated at least one positive reaction to a patch test, 66.7% of which were clinically relevant. Allergic contact dermatitis was diagnosed in 45.5% of patients. Independent factors predisposing towards facial dermatitis were female sex, having a previous history of cosmetic allergy, a positive patch test reaction to hairdressing product-related allergens, and a positive allergic reaction to preservative allergens.

CONCLUSIONS

The prevalence of facial dermatitis was 27.4%. Almost half of all patients with facial dermatitis demonstrated ACD. Factors associated with facial ACD were female gender, a history of cosmetic allergy, and positive patch test reactions to hairdressing product-related allergens and preservatives.

摘要

背景

面部皮炎在皮肤科临床实践中较为常见。有时难以处理,因为其致病因素可能多种多样且难以诊断。

目的

本研究旨在确定转诊至接触性皮炎诊所的面部皮炎患者的特征、斑贴试验结果及最终诊断,并确定与面部过敏性接触性皮炎(ACD)相关的因素。

方法

我们回顾性分析了2006年7月至2011年6月期间在该诊所接受斑贴试验的面部皮炎患者的病例记录。

结果

在891例接受斑贴试验的患者中,244例(27.4%)患有面部皮炎。女性患者比男性患者多9.1倍。患者的平均年龄±标准差为37.3±14.8岁。共有199例(81.6%)患者斑贴试验至少有一项阳性反应,其中66.7%与临床相关。45.5%的患者被诊断为过敏性接触性皮炎。面部皮炎的独立易患因素为女性、有化妆品过敏史、对美发产品相关过敏原斑贴试验反应阳性以及对防腐剂过敏原过敏反应阳性。

结论

面部皮炎的患病率为27.4%。几乎一半的面部皮炎患者表现为ACD。与面部ACD相关的因素为女性、化妆品过敏史以及对美发产品相关过敏原和防腐剂斑贴试验反应阳性。

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