霍奇金淋巴瘤青少年及青年幸存者的运动与疲劳：来自儿童肿瘤学组的报告
Exercise and Fatigue in Adolescent and Young Adult Survivors of Hodgkin Lymphoma: A Report from the Children's Oncology Group.
作者信息
Macpherson Catherine Fiona, Hooke Mary C, Friedman Debra L, Campbell Kristin, Withycombe Janice, Schwartz Cindy L, Kelly Kara, Meza Jane
机构信息
Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles , Los Angeles, California.
School of Nursing, University of Minnesota School of Nursing , Minneapolis, Minnesota.
出版信息
J Adolesc Young Adult Oncol. 2015 Sep;4(3):137-40. doi: 10.1089/jayao.2015.0013.
Fatigue is a significant problem for adolescent and young adult (AYA) Hodgkin lymphoma (HL) survivors. The relationship between exercise and fatigue is complex. This study explored the trajectory of and the relationship between exercise and fatigue over 36 months post-therapy in a cohort of 103 AYA-aged HL survivors treated on Children's Oncology Group (COG) study AHOD0031. Descriptive statistics and generalized estimating equations were used in this secondary data analysis. Exercise and fatigue improved over time but were unrelated; amount of exercise at end of therapy predicted amount of exercise at 12 (p = 0.02) and 36 (p = 0.0008) months post-therapy.
疲劳是青少年和青年霍奇金淋巴瘤（HL）幸存者面临的一个重大问题。运动与疲劳之间的关系很复杂。本研究在103名接受儿童肿瘤学组（COG）AHOD0031研究治疗的青少年和青年HL幸存者队列中，探讨了治疗后36个月内运动与疲劳的轨迹及其关系。在这项二次数据分析中使用了描述性统计和广义估计方程。运动和疲劳随时间改善，但两者无关；治疗结束时的运动量可预测治疗后12个月（p = 0.02）和36个月（p = 0.0008）的运动量。
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