万古霉素敏感性可变的肠球菌菌血症
Vancomycin-Variable Enterococcal Bacteremia.
作者信息
Downing M A, Xiong J, Eshaghi A, McGeer A, Patel S N, Johnstone J
机构信息
St. Joseph's Health Centre, Toronto, ON, Canada Department of Medicine, University of Toronto, Toronto, ON, Canada.
St. Joseph's Health Centre, Toronto, ON, Canada.
出版信息
J Clin Microbiol. 2015 Dec;53(12):3951-3. doi: 10.1128/JCM.02046-15. Epub 2015 Sep 30.
Abstract
Vancomycin-variable enterococcus (VVE) is an emerging pathogen. VVE isolates initially appear phenotypically susceptible to vancomycin but possesses the vanA gene and can develop in vitro and in vivo resistance to vancomycin. We report a case of VVE bacteremia and describe how VVE poses diagnostic and therapeutic dilemmas.
摘要
万古霉素可变肠球菌（VVE）是一种新出现的病原体。VVE分离株最初在表型上似乎对万古霉素敏感，但携带vanA基因，并且可在体外和体内产生对万古霉素的耐药性。我们报告了1例VVE菌血症病例，并描述了VVE如何带来诊断和治疗方面的难题。
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Antimicrob Agents Chemother. 2015 Mar;59(3):1405-10. doi: 10.1128/AAC.04490-14. Epub 2014 Dec 15.
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Vancomycin-variable Enterococcus faecium: in vivo emergence of vancomycin resistance in a vancomycin-susceptible isolate.万古霉素敏感性可变的屎肠球菌：一株对万古霉素敏感的分离株中万古霉素耐药性的体内出现
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J Antimicrob Chemother. 2011 Dec;66(12):2758-62. doi: 10.1093/jac/dkr379. Epub 2011 Sep 15.
6
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