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1
Antimicrobial resistance surveillance in Canadian hospitals, 2007-2012.2007 - 2012年加拿大医院抗菌药物耐药性监测
Can Commun Dis Rep. 2014 Nov 7;40(Suppl 2):6-13. doi: 10.14745/ccdr.v40is2a02.
2
Vancomycin-variable enterococci can give rise to constitutive resistance during antibiotic therapy.万古霉素可变肠球菌在抗生素治疗期间可产生组成性耐药。
Antimicrob Agents Chemother. 2015 Mar;59(3):1405-10. doi: 10.1128/AAC.04490-14. Epub 2014 Dec 15.
3
Vancomycin-variable Enterococcus faecium: in vivo emergence of vancomycin resistance in a vancomycin-susceptible isolate.万古霉素敏感性可变的屎肠球菌:一株对万古霉素敏感的分离株中万古霉素耐药性的体内出现
J Clin Microbiol. 2014 May;52(5):1766-7. doi: 10.1128/JCM.03579-13. Epub 2014 Feb 12.
4
Outbreak of vancomycin-susceptible Enterococcus faecium containing the wild-type vanA gene.含有野生型vanA基因的万古霉素敏感粪肠球菌暴发。
J Clin Microbiol. 2014 May;52(5):1682-6. doi: 10.1128/JCM.03563-13. Epub 2014 Feb 12.
5
vanA-containing Enterococcus faecium susceptible to vancomycin and teicoplanin because of major nucleotide deletions in Tn1546.对万古霉素和替考拉宁敏感的含 vanA 肠球菌,是由于 Tn1546 中的主要核苷酸缺失。
J Antimicrob Chemother. 2011 Dec;66(12):2758-62. doi: 10.1093/jac/dkr379. Epub 2011 Sep 15.
6
Secular trends of hospitalization with vancomycin-resistant enterococcus infection in the United States, 2000-2006.2000 - 2006年美国耐万古霉素肠球菌感染的住院治疗长期趋势
Infect Control Hosp Epidemiol. 2009 Feb;30(2):184-6. doi: 10.1086/593956.
7
Vancomycin-resistant enterococci.耐万古霉素肠球菌
Clin Microbiol Rev. 2000 Oct;13(4):686-707. doi: 10.1128/CMR.13.4.686.

万古霉素敏感性可变的肠球菌菌血症

Vancomycin-Variable Enterococcal Bacteremia.

作者信息

Downing M A, Xiong J, Eshaghi A, McGeer A, Patel S N, Johnstone J

机构信息

St. Joseph's Health Centre, Toronto, ON, Canada Department of Medicine, University of Toronto, Toronto, ON, Canada.

St. Joseph's Health Centre, Toronto, ON, Canada.

出版信息

J Clin Microbiol. 2015 Dec;53(12):3951-3. doi: 10.1128/JCM.02046-15. Epub 2015 Sep 30.

DOI:10.1128/JCM.02046-15
PMID:26424845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4652112/
Abstract

Vancomycin-variable enterococcus (VVE) is an emerging pathogen. VVE isolates initially appear phenotypically susceptible to vancomycin but possesses the vanA gene and can develop in vitro and in vivo resistance to vancomycin. We report a case of VVE bacteremia and describe how VVE poses diagnostic and therapeutic dilemmas.

摘要

万古霉素可变肠球菌(VVE)是一种新出现的病原体。VVE分离株最初在表型上似乎对万古霉素敏感,但携带vanA基因,并且可在体外和体内产生对万古霉素的耐药性。我们报告了1例VVE菌血症病例,并描述了VVE如何带来诊断和治疗方面的难题。