Barroso Eliane Marçon, Carvalho André Lopes, Paiva Carlos Eduardo, Murphy Barbara A, Paiva Bianca Sakamoto Ribeiro
Research Group on Palliative Care and Health-Related Quality of Life (GPQual), Stricto Sensu Graduate Program in Oncology, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
Fundação Pio XII, Barretos Cancer Hospital, Barretos, São Paulo, Brazil.
BMC Res Notes. 2015 Oct 1;8:522. doi: 10.1186/s13104-015-1470-8.
Patients who undergo radiotherapy to treat head and neck cancer can present with several symptoms, including oral ones. The symptoms are usually assessed using instruments to evaluate quality of life. However, these instruments do not really assess oral health outcomes and their functional implications. The VHNSS 2.0 instrument was developed to be used with head and neck cancer patients, and has recently been translated and culturally adapted to be used in Brazil. The purpose of the study was to evaluate the psychometric properties of the VHNSS 2.0 Brazilian Portuguese version.
Three assessment instruments, the Brazilian Portuguese versions of EORTC QLQ-C30, EORTC H&N 35 and VHNSS 2.0, were answered by 241 head and neck cancer patients, of whom 47 were submitted to the test retest in 5-16 days. The construct validity was assessed through convergent validation (assuming correlations between VHNSS 2.0 and EORTC), and known group analysis (radiotherapy time, site of tumor, staging and surgery). Reliability was evaluated by means of Cronbach's alpha and test retest using the intraclass correlation coefficient.
241 head and neck cancer patients, median age 58.8, were included in this study. Hypothesized correlations were confirmed, the comparison among the groups showed differences in most of the domains. Reliability for the domains of swallowing solids, dry mouth, mouth pain, mucus, voice, pain and taste/smell presented Cronbach's alpha values from 0.858 to 0.735 and for the domains of nutrition, swallowing liquids and teeth, 0.618, 0.620 and 0.670 respectively. The test-retest reliability, for the domains of the VHNSS 2.0, measured using intraclass correlation coefficient, ranged from 0.372 to 0.854.
The VHNSS 2.0 Brazilian Portuguese version presented good results for the convergent validation and known-group analyses. It also showed reliability for the Cronbach´s alpha and test retest for most domains.
接受放射治疗的头颈癌患者可能会出现多种症状，包括口腔症状。这些症状通常使用评估生活质量的工具进行评估。然而，这些工具并未真正评估口腔健康结果及其功能影响。VHNSS 2.0工具专为头颈癌患者设计，最近已被翻译成巴西葡萄牙语并进行文化适应性调整，以便在巴西使用。本研究的目的是评估VHNSS 2.0巴西葡萄牙语版本的心理测量特性。
241名头颈癌患者回答了三种评估工具，即巴西葡萄牙语版的EORTC QLQ-C30、EORTC H&N 35和VHNSS 2.0，其中47名患者在5-16天内接受了重测。通过收敛效度（假设VHNSS 2.0与EORTC之间存在相关性）和已知组分析（放疗时间、肿瘤部位、分期和手术）评估结构效度。通过Cronbach's alpha系数和使用组内相关系数的重测来评估信度。
本研究纳入了241名头颈癌患者，中位年龄为58.8岁。假设的相关性得到证实，组间比较显示大多数领域存在差异。吞咽固体、口干、口腔疼痛、黏液、声音、疼痛和味觉/嗅觉领域的Cronbach's alpha值在0.858至0.735之间，营养、吞咽液体和牙齿领域的Cronbach's alpha值分别为0.618、0.620和0.670。使用组内相关系数测量的VHNSS 2.0各领域的重测信度在0.372至0.854之间。
VHNSS 2.0巴西葡萄牙语版本在收敛效度和已知组分析方面取得了良好结果。它在大多数领域的Cronbach's alpha系数和重测中也显示出信度。
