Um Yoo-Jin, Oh Seung-Won, Lee Cheol-Min, Kwon Hyuk-Tae, Joh Hee-Kyung, Kim Young-Ju, Kim Hyun-Joo, Ahn Sang-Hyun
Department of Family Medicine, Seoul National University Hospital, Seoul, Korea.
Department of Family Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, Korea.
Korean J Fam Med. 2015 Sep;36(5):245-52. doi: 10.4082/kjfm.2015.36.5.245. Epub 2015 Sep 18.
The effect of dietary fat intake on the risk of cardiovascular disease remains unclear. We investigated the association between dietary fat and specific types of fat intake and the risk of metabolic syndrome.
The study population included 1,662 healthy adults who were 50.2 years of age and had no known hypertension, diabetes, hyperlipidemia, or metabolic syndrome at the initial visit. Dietary intake was obtained from a 1-day food record. During 20.7 months of follow-up, we documented 147 cases of metabolic syndrome confirmed by self-report, anthropometric data, and blood test results. The intakes of total fat, vegetable fat, animal fat, saturated fatty acid (SFA), polyunsaturated fatty acid (PUFA), monounsaturated fatty acid (MUFA), and cholesterol level divided by quintile. Multivariate analyses included age, sex, body mass index, smoking status, alcohol intake, physical activity, total calorie, and protein intake.
Vegetable fat intake was inversely associated with metabolic syndrome risk (odds ratio for the highest vs. the lowest quintile, 0.33; 95% confidence interval, 0.14 to 0.76). Total fat, animal fat, SFA, PUFA, MUFA, and cholesterol intakes showed no association with metabolic syndrome. Vegetable fat intake was inversely associated with the risk of hypertriglyceridemia among the components of metabolic syndrome.
These data support an inverse association between vegetable fat and the risk of metabolic syndrome.
膳食脂肪摄入对心血管疾病风险的影响仍不明确。我们调查了膳食脂肪及特定类型脂肪摄入与代谢综合征风险之间的关联。
研究人群包括1662名健康成年人，他们初次就诊时年龄为50.2岁，无已知的高血压、糖尿病、高脂血症或代谢综合征。膳食摄入量通过1天的饮食记录获得。在20.7个月的随访期间，我们记录了147例经自我报告、人体测量数据和血液检测结果确诊的代谢综合征病例。将总脂肪、植物脂肪、动物脂肪、饱和脂肪酸（SFA）、多不饱和脂肪酸（PUFA）、单不饱和脂肪酸（MUFA）的摄入量以及胆固醇水平按五分位数划分。多变量分析包括年龄、性别、体重指数、吸烟状况、酒精摄入量、身体活动、总热量和蛋白质摄入量。
植物脂肪摄入与代谢综合征风险呈负相关（最高五分位数与最低五分位数的比值比为0.33；95%置信区间为0.14至0.76）。总脂肪、动物脂肪、SFA、PUFA、MUFA和胆固醇摄入量与代谢综合征无关联。在代谢综合征的各组分中，植物脂肪摄入与高甘油三酯血症风险呈负相关。
这些数据支持植物脂肪与代谢综合征风险之间存在负相关。
