Çekmez Yasemin, Şanlıkan Fatih, Göçmen Ahmet, Vural Aylin, Türkmen Simge Bağcı
Department of Obstetrics and Gynaecology, Umraniye Medical and Research Hospital, Istanbul, Turkey.
Med Princ Pract. 2016;25(1):8-11. doi: 10.1159/000441433. Epub 2015 Oct 27.
To evaluate the success rates and clinical outcomes of cervical cryotherapy applied to cervical ectopy for symptomatic relief.
A total of 124 women who underwent cryotherapy for symptomatic treatment of cervical ectopy were included in this study. Indications for treatment were: abundant leucorrhoea (n = 114), post-coital bleeding (n = 22), recurrent cervicitis (n = 30) and pelvic pain (n = 12). Cryotherapy consisted of the use of carbon dioxide at -89°C to destroy the ectopic columnar epithelium by freezing, and it was transmitted to the ectopy through a flat cryoprobe. No routine anaesthesia or analgesia was administered. All patients were questioned about the status of their symptoms after 6 weeks of treatment.
The highest success rate was obtained in patients with abundant leucorrhoea (n = 102; 89.5%), while the lowest success rate was achieved in subjects with pelvic pain (n = 7; 58%). After treatment, no severe complications were observed, except for hydrorrhoea for a few days. Success rates were 9 times lower in patients who had 3 or more cervicitis episodes per 6 months.
In this study, the success rate of cryotherapy was highest in patients with abundant leucorrhoea and lowest in patients with pelvic pain and recurrent cervicitis. Hence, we recommend that clinicians perform the procedure in such patients without much delay.
评估应用于宫颈异位以缓解症状的宫颈冷冻疗法的成功率及临床效果。
本研究纳入了124例因宫颈异位症状性治疗而接受冷冻疗法的女性。治疗指征包括：白带过多（n = 114）、性交后出血（n = 22）、复发性宫颈炎（n = 30）及盆腔疼痛（n = 12）。冷冻疗法是利用-89°C的二氧化碳通过冷冻破坏异位柱状上皮，并通过扁平冷冻探头将其传递至异位处。未给予常规麻醉或镇痛。所有患者在治疗6周后均被询问症状情况。
白带过多的患者成功率最高（n = 102；89.5%），而盆腔疼痛的患者成功率最低（n = 7；58%）。治疗后，除少数几天出现水样白带外，未观察到严重并发症。每6个月有3次或更多宫颈炎发作的患者成功率低9倍。
在本研究中，冷冻疗法在白带过多的患者中成功率最高，在盆腔疼痛和复发性宫颈炎的患者中成功率最低。因此，我们建议临床医生在这类患者中尽快进行该操作。
