Profeta Andrea Corrado, Prucher Gian Marco
Department of Restorative Dentistry, Biomaterials Science, Biomimetics and Biophotonics (B3) Research Group, King's College London Dental Institute.
Dent Mater J. 2015;34(5):559-71. doi: 10.4012/dmj.2014-233.
Bioactive-glass (B-G) is a material known for its favorable biological response when in contact with surrounding fibro-osseous tissues, due not only to an osteoconductive property, but also to an osteostimulatory capacity, and superior biocompatibility for use in human body. The objectives of this paper are to review recent studies on B-G in periodontal and implant therapy, describing its basic properties and mechanism of activity as well as discoursing about state of art and future perspective of utilization. From a demonstrated clinical benefit as bone graft for the elimination of osseous defects due to periodontal disease (intrabony/furcation defects) and surgeries (alveolar ridge preservation, maxillary sinus augmentation), to a potential use for manufacturing bioactive dental implants, possibly allowing wider case selection criteria together with improved integration rates even in the more challenging osteoporotic and medically compromised patients, this biomaterial represents an important field of study with high academic, clinical and industrial importance.
生物活性玻璃(B-G)是一种材料,当与周围的纤维骨组织接触时,因其不仅具有骨传导性,还具有骨刺激能力,以及在人体使用时的卓越生物相容性,而以其良好的生物学反应而闻名。本文的目的是回顾近期关于生物活性玻璃在牙周和种植治疗方面的研究,描述其基本特性和活性机制,并论述其应用的现状和未来前景。从作为骨移植材料用于消除牙周疾病(骨内/根分叉缺损)和手术(牙槽嵴保存、上颌窦提升)导致的骨缺损所显示出的临床益处,到用于制造生物活性牙科种植体的潜在用途,这可能允许更广泛的病例选择标准,甚至在更具挑战性的骨质疏松和有医学问题的患者中提高整合率,这种生物材料代表了一个具有高度学术、临床和工业重要性的重要研究领域。