Henriksen Daniel Pilsgaard, Rasmussen Lotte, Hansen Morten Rix, Hallas Jesper, Pottegård Anton
Department of Respiratory Medicine, Odense University Hospital DK-5000 Odense C, Denmark.
Clinical Pharmacology, Department of Public Health, University of Southern Denmark, Odense, Denmark.
PLoS One. 2015 Oct 6;10(10):e0140197. doi: 10.1371/journal.pone.0140197. eCollection 2015.
While Denmark is well known for its plethora of registers. Many studies are conducted on research databases that only cover parts of Denmark, and regional differences could potentially threaten these studies' external validity. The aim of this study was to assess sociodemographic and health related homogeneity of the five Danish regions.
We obtained descriptive data for the five Danish regions, using publicly available data sources: Statbank Denmark, the Danish Ministry of Economic Affairs, and Medstat.dk. These data sources comprise aggregate data from four different nationwide registers: The Danish National Patient Register, The Danish Civil Registration System, The Danish Register of Medicinal Product Statistics, and The Danish National Health Service Register for Primary Care. We compared the Danish regions regarding demographic and socioeconomic characteristics, health care utilization, and use of medication. For each characteristic, one-year prevalence was obtained and analyses were performed for 2013 and 2008 to account for possible change over time.
In 2013, 5,602,628 persons were living in Denmark. The mean age was 40.7 years in the entire Danish population and ranged between 39.6 to 42.4 years in the five regions (coefficient of variation between regions [CV] = 0.028). The proportion of women in Denmark was 50.4% (CV = 0.009). The proportion of residents with low education level was 28.7% (CV = 0.051). The annual number of GP contacts was 7.1 (range: 6.7-7.4, CV = 0.040), and 114 per 1,000 residents were admitted to the hospital (range: 101-131, CV = 0.107). The annual number of persons redeeming a prescription of any medication was 723 per 1,000 residents (range: 718-743, CV = 0.016). Analyses for 2008 showed comparable levels of homogeneity as for 2013.
We found substantial homogeneity between all of the five Danish regions with regard to sociodemographic and health related characteristics. Epidemiologic studies conducted on regional subsets of Danish citizens have a high degree of generalizability.
丹麦以其众多的登记册而闻名。许多研究是在仅覆盖丹麦部分地区的研究数据库上进行的，区域差异可能会威胁到这些研究的外部有效性。本研究的目的是评估丹麦五个地区在社会人口统计学和健康方面的同质性。
我们使用公开可用的数据源获取了丹麦五个地区的描述性数据：丹麦统计局、丹麦经济事务部和Medstat.dk。这些数据源包括来自四个不同的全国性登记册的汇总数据：丹麦国家患者登记册、丹麦民事登记系统、丹麦药品统计登记册和丹麦国家初级保健服务登记册。我们比较了丹麦各地区在人口统计学和社会经济特征、医疗保健利用情况以及药物使用方面的差异。对于每个特征，获取了一年的患病率，并对2013年和2008年进行了分析，以考虑随时间可能发生的变化。
2013年，丹麦有5,602,628人居住。丹麦全体人口的平均年龄为40.7岁，五个地区的平均年龄在39.6岁至42.4岁之间（地区间变异系数[CV]=0.028）。丹麦女性的比例为50.4%（CV=0.009）。低教育水平居民的比例为28.7%（CV=0.051）。全科医生每年的诊疗次数为7.1次（范围：6.7 - 7.4次，CV=0.040），每1000名居民中有114人住院（范围：101 - 131人，CV=0.107）。每1000名居民中每年开具任何药物处方的人数为723人（范围：718 - 743人，CV=0.016）。2008年的分析显示，同质性水平与2013年相当。
我们发现丹麦所有五个地区在社会人口统计学和健康相关特征方面具有高度同质性。对丹麦公民区域子集进行的流行病学研究具有高度的普遍性。
