Lynch M D, Bashir S
a Department of Dermatology , King's College Hospital , Denmark Hill , London , UK.
J Dermatolog Treat. 2016;27(3):285-9. doi: 10.3109/09546634.2015.1094178. Epub 2015 Oct 14.
Platelet-rich plasma (PRP) is an autologous blood-derived product enriched in platelets, growth factors, chemokines and cytokines. Initial applications were predominantly in musculoskeletal and maxillofacial fields, however in recent years, it has been used for a range of dermatological indications including wound healing, fat grafting, alopecia, scar revision and dermal volume augmentation. Here, we critically appraise the literature relating to the usage of PRP within Dermatology. We have evaluated in vitro data, preclinical animal studies and human trials. We conclude that, whilst the literature may be consistent with a modest benefit for specific indications, there is not sufficient evidence supporting the efficacy of PRP to justify a role in routine dermatological practice at the present time. However, since PRP is generally well tolerated with few reported complications, further study may be justified in the context of organized trials.
富血小板血浆（PRP）是一种自体血液衍生产品，富含血小板、生长因子、趋化因子和细胞因子。最初主要应用于肌肉骨骼和颌面领域，然而近年来，它已被用于一系列皮肤科适应症，包括伤口愈合、脂肪移植、脱发、瘢痕修复和真皮容量增加。在此，我们对皮肤科领域中PRP使用的相关文献进行批判性评估。我们评估了体外数据、临床前动物研究和人体试验。我们得出结论，虽然文献可能表明PRP对特定适应症有一定益处，但目前没有足够证据支持PRP的疗效，不足以证明其在常规皮肤科实践中的作用。然而，由于PRP通常耐受性良好，报告的并发症较少，在有组织的试验背景下进行进一步研究可能是合理的。
